1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Protease Inhibitors
  4. Serpin (Protease Inhibitor)
  5. Serpin B10
  6. SERPINB10 Protein, Mouse (sf9, His)

SERPINB10 Protein, Mouse (sf9, His)

Cat. No.: HY-P77196
COA Handling Instructions

SERPINB10 is an important protease inhibitor that may regulate protease activity in hematopoiesis and TNF-induced apoptosis. SERPINB10 acts in both the cytoplasm and the nucleus, demonstrating versatility in influencing key cellular processes. SERPINB10 Protein, Mouse (sf9, His) is the recombinant mouse-derived SERPINB10 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SERPINB10 Protein, Mouse (sf9, His) is 397 a.a., with molecular weight of ~44 kDa.

For research use only. We do not sell to patients.

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  • Biological Activity

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Description

SERPINB10 is an important protease inhibitor that may regulate protease activity in hematopoiesis and TNF-induced apoptosis. SERPINB10 acts in both the cytoplasm and the nucleus, demonstrating versatility in influencing key cellular processes. SERPINB10 Protein, Mouse (sf9, His) is the recombinant mouse-derived SERPINB10 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SERPINB10 Protein, Mouse (sf9, His) is 397 a.a., with molecular weight of ~44 kDa.

Background

SERPINB10 emerges as a notable protease inhibitor with potential regulatory roles in protease activities during hematopoiesis and apoptosis induced by TNF. This protein is suggested to modulate protease activities in both the cytoplasm and the nucleus, indicating its versatility in influencing key cellular processes. The precise mechanisms through which SERPINB10 contributes to the regulation of protease activities underscore its significance in cellular homeostasis and apoptotic pathways, particularly in the context of hematopoietic processes and TNF-induced responses.

Species

Mouse

Source

Sf9 insect cells

Tag

C-His

Accession

Q8K1K6 (M1-P397)

Gene ID

241197  [NCBI]

Molecular Construction
N-term
SERPINB10 (M1-P397)
Accession # Q8K1K6
His
C-term
Synonyms
Serpin B10; Bomapin; Peptidase inhibitor 10; PI-10
Molecular Weight

Approximately 44 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE

Appearance

Solution.

Formulation

Supplied as a 0.22 μm filtered solution of 50 mM Tris, 100 mM NaCl, pH 8.0

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

SERPINB10 Protein, Mouse (sf9, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SERPINB10 Protein, Mouse (sf9, His)
Cat. No.:
HY-P77196
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