STAT5A Protein, Human (sf9, His)
STAT5A Protein, Human (sf9, His) is the recombinant human-derived STAT5, expressed by Sf9 insect cells , with His labeled tag. ,
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
STAT5A Protein, Human (sf9, His) is the recombinant human-derived STAT5, expressed by Sf9 insect cells , with His labeled tag. ,
STAT5 performs a dual function: signal transduction and activation of transcription. It mediates cellular responses to the cytokine KITLG/SCF and other growth factors, as well as responses to ERBB4. STAT5 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3, and FGFR4. It binds to the GAS element and activates PRL-induced transcription. During lactation, STAT5 regulates the expression of milk proteins. by similar: STAT5 is also involved in mediating cellular responses to other growth factors and may play roles in multiple signaling pathways.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag His
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Accession
P42229-1 (M1-S794)
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Gene ID6776
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Protein Length
Full Length of Isoform-1
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Synonyms
STAT5A; MGF; Prev. STAT5; Epididymis Secretory Sperm Binding Protein; Signal Transducer And Activator Of Transcription 5A; Signal Transducer And Activator Of Transcription
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AA Sequence
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRLGDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGGSSATYMDQAPSPAVCPQAPYNMYPQNPDHVLDQDGEFDLDETMDVARHVEELLRRPMDSLDSRLSPPAGLFTSARGSLS
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Molecular Weight
Approximately 92 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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