Syntaxin-3 Protein, Human (His)
Syntaxin-3 protein plays a potentially critical role in docking synaptic vesicles at the presynaptic zone, suggesting a role in regulating neurotransmitter release. Furthermore, it is also implicated as an apical receptor in apical vesicle membrane fusion, suggesting a broader involvement in intracellular trafficking. Syntaxin-3 Protein, Human (His) is the recombinant human-derived Syntaxin-3 protein, expressed by E. coli , with N-His labeled tag.
- Species: Human
- Source: E. coli
Biological Activity
Syntaxin-3 protein plays a potentially critical role in docking synaptic vesicles at the presynaptic zone, suggesting a role in regulating neurotransmitter release. Furthermore, it is also implicated as an apical receptor in apical vesicle membrane fusion, suggesting a broader involvement in intracellular trafficking. Syntaxin-3 Protein, Human (His) is the recombinant human-derived Syntaxin-3 protein, expressed by E. coli , with N-His labeled tag.
Syntaxin-3 Protein emerges as a potential key player in the docking of synaptic vesicles at presynaptic active zones, indicating its probable role in regulating neurotransmitter release. Additionally, it is implicated as an apical receptor involved in the membrane fusion of apical vesicles, suggesting a broader involvement in intracellular vesicle trafficking and fusion processes. Notably, Syntaxin-3 is deemed essential for the survival of retinal photoreceptors, underlining its critical role in maintaining the structural and functional integrity of these specialized cells. The diverse functions attributed to Syntaxin-3 underscore its significance in neuronal signaling and cellular processes, warranting further exploration to unravel the specific molecular mechanisms underlying its involvement in synaptic function and retinal homeostasis.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-His
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Accession
Q13277 (M1-N289)
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Molecular Construction
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N-term
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His
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Syntaxin-3 (M1-N289)
Accession # Q13277 -
C-term
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Protein Length
Full Length
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Synonyms
N-Syndecan; SDC3; SDCN; Syndecan-3; SYND3syndecan proteoglycan 3
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AA Sequence
MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGLN
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Predicted Molecular Mass
32.4 kDa
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Molecular Weight
Approximately 37 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)