TMIGD2 Protein, Human (HEK293, Fc)

TMIGD2, a multifaceted protein, actively participates in cellular processes, including cell-cell interaction, migration, and angiogenesis. Its interaction with HHLA2 enhances T-cell proliferation and cytokine production through AKT-dependent signaling during TCR-mediated activation. TMIGD2 may engage in homophilic interactions, regulating cell-cell communication. Interactions with CACNB2, DST, MIA, and NCKIPSD indicate its involvement in diverse cellular pathways, emphasizing its versatile functions in essential activities. TMIGD2 Protein, Human (HEK293, Fc) is the recombinant human-derived TMIGD2 protein, expressed by HEK293, with C-hFc labeled tag. The total length of TMIGD2 Protein, Human (HEK293, Fc) is 150 a.a., with molecular weight of ~40.9 KDa.

TMIGD2, a multifaceted protein, actively participates in various cellular processes such as cell-cell interaction, cell migration, and angiogenesis. Its interaction with HHLA2 highlights its role in costimulating T-cells during TCR-mediated activation, thereby enhancing T-cell proliferation and cytokine production through an AKT-dependent signaling cascade. TMIGD2 may also engage in homophilic interactions, potentially regulating cell-cell communication. Additionally, it forms interactions with CACNB2, DST, MIA, and NCKIPSD, indicating its involvement in diverse cellular pathways and signaling networks. These interactions collectively underscore the versatile functions of TMIGD2 in orchestrating essential cellular activities.

Human

HEK293

C-hFc

Q96BF3 (M1-G150)

126259  [NCBI]

Approximately 40.9 kDa.

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.