Renin inhibitor-1
Renin inhibitor-1 (compound 26) is a potent and orally active renin inhibitor with IC50s of 0.9, 1.8 nM for rh-renin and hPRA, respectively. Renin inhibitor-1 shows antihypertensive efficacy. Renin inhibitor-1 has the potential for the research of hypertension and cardiovascular/renal diseases.
For research use only. We do not sell to patients.
- CAS No.: 1093082-54-2
- Formula: C22H30N4O4
- Molecular Weight:414.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 0.9 nM (rh-renin); 1.8 nM (hPRA)[1]
Chemical Information
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CAS No. 1093082-54-2
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Molecular Weight 414.50
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Formula C22H30N4O4
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SMILES
O=C(OC)NCCCN1C=C(CN(C2CC2)C([C@H]3CNCCO3)=O)C4=C1C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)