Resorufin pentyl ether
Based on 1 Customer Validation
Resorufin pentyl ether (Pentoxyresorufin) is a Resazurin (HY-111391) analogue. Resorufin pentyl ether can function as a substrate probe to characterize and differentiate between a variety of inducers of cytochromes P-450. Resorufin pentyl ether has bactericidal activity against N. gonorrhoeae.
For research use only. We do not sell to patients.
- Purity : 98.16%
- CAS No.: 87687-03-4
- Formula: C17H17NO3
- Molecular Weight:283.32
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-D0145
7-EthoxyresorufinCytochrome P450 Inhibitor -
HY-D0144
Resorufin methyl etherCytochrome P453 Substrate -
HY-D0055
3-Cyano-7-ethoxycoumarinCytochrome P-450 Substrate -
HY-103389
1-AminobenzotriazoleCytochrome P450 Inhibitor -
HY-N0125
DiosmetinCytochrome P450 Inhibitor -
HY-119403
4-Phenyl-1,2,3-thiadiazoleCYP2B4/CYP2E1 Inhibitor -
HY-105184
YM511Aromatase Inhibitor -
HY-10493
CobicistatCYP3A Inhibitor -
HY-19340
TMSCYP1B1 Inhibitor -
HY-124265
4β-HydroxycholesterolDrug Metabolite -
HY-N8354
6',7'-DihydroxybergamottinCYP3A4 Inhibitor -
HY-N0125R
Diosmetin (Standard)
Biological Activity
Description
Emission (Em)
460
Excitation (Ex)
335
Chemical Information
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CAS No. 87687-03-4
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Appearance Solid
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Molecular Weight 283.32
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Formula C17H17NO3
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Color Orange to red
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SMILES
O=C1C=CC2=NC3=C(C=C(OCCCCC)C=C3)OC2=C1
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Synonyms
Pentoxyresorufin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMF : 5 mg/mL (17.65 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Bacterial live/dead nucleic-acid viability staining
The LIVE/DEAD bacterial viability staining method is based on differential permeability of nucleic-acid-binding fluorescent dyes, most commonly SYTO 9 and propidium iodide (PI), which enables discrimination of bacterial populations with intact versus compromised cytoplasmic membranes. SYTO 9 penetrates both intact and damaged bacterial membranes and binds nucleic acids to produce green fluorescence, whereas propidium iodide penetrates only cells with compromised membranes and fluoresces red while also reducing SYTO 9 signal through competitive binding and fluorescence interactions. The resulting fluorescence pattern is interpreted as a proxy for membrane integrity, which is widely used as an indicator of bacterial viability in microscopy, flow cytometry, and spectroscopic platforms. However, mechanistic studies show that SYTO 9 and PI interactions involve displacement and fluorescence resonance energy transfer effects, which can influence signal interpretation depending on dye ratios a
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Deanna M. Schmitt, et al. Antibacterial activity of resazurin-based compounds against Neisseria gonorrhoeae in vitro and in vivo. Int J Antimicrob Agents. 2016 Oct; 48(4): 367–372. [Content Brief]
[2]. M D Burke, et al. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. Biochem Pharmacol. 1985 Sep 15;34(18):3337-45. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 3.5296 mL | 17.6479 mL | 35.2958 mL | 88.2394 mL |
| 5 mM | 0.7059 mL | 3.5296 mL | 7.0592 mL | 17.6479 mL | |
| 10 mM | 0.3530 mL | 1.7648 mL | 3.5296 mL | 8.8239 mL | |
| 15 mM | 0.2353 mL | 1.1765 mL | 2.3531 mL | 5.8826 mL |
Resorufin pentyl ether Related Classifications
HY-D0147 Related Classifications
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