2. Apoptosis
  3. RIP kinase
  4. RIPK1-IN-10

RIPK1-IN-10 is a potent RIPK1 inhibitor, example 37, extracted from patent WO2021160109.

For research use only. We do not sell to patients.

RIPK1-IN-10 Chemical Structure

RIPK1-IN-10 Chemical Structure

CAS No. : 2682889-51-4

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 638 In-stock
Solution
10 mM * 1 mL in DMSO USD 638 In-stock
Solid
5 mg USD 580 In-stock
10 mg USD 1050 In-stock
25 mg USD 2250 In-stock
50 mg USD 3500 In-stock
100 mg USD 5600 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

RIPK1-IN-10 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

RIPK1-IN-10 is a potent RIPK1 inhibitor, example 37, extracted from patent WO2021160109[1].

Molecular Weight

574.58

Formula

C30H28F2N6O4
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(C1CC1)NC2=CN3N=C(C4=CC5=C(N=C4)CCN(CC6=CC(F)=CC(F)=C6OC7CCOCC7)C5=O)C=CC3=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (54.39 mM; ultrasonic and warming and heat to 70°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7404 mL 8.7020 mL 17.4040 mL
5 mM 0.3481 mL 1.7404 mL 3.4808 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7404 mL 8.7020 mL 17.4040 mL 43.5100 mL
5 mM 0.3481 mL 1.7404 mL 3.4808 mL 8.7020 mL
10 mM 0.1740 mL 0.8702 mL 1.7404 mL 4.3510 mL
15 mM 0.1160 mL 0.5801 mL 1.1603 mL 2.9007 mL
20 mM 0.0870 mL 0.4351 mL 0.8702 mL 2.1755 mL
25 mM 0.0696 mL 0.3481 mL 0.6962 mL 1.7404 mL
30 mM 0.0580 mL 0.2901 mL 0.5801 mL 1.4503 mL
40 mM 0.0435 mL 0.2176 mL 0.4351 mL 1.0878 mL
50 mM 0.0348 mL 0.1740 mL 0.3481 mL 0.8702 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

RIPK1-IN-10 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RIPK1-IN-102682889-51-4RIP kinaseReceptor-interacting protein kinasesRIPKInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
RIPK1-IN-10
Cat. No.:
HY-143728
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.