Ro 25-0534
Based on 1 Customer Validation
Ro 25-0534 is an antimicrobial compound against Pseudomonas. Ro 25-0534 is active against Enterobacteriaceae (MIC90: 0.06-2 μg/mL), Oxacillin (HY-B0465)-susceptible staphylococci, β-hemolytic streptococci, and penicillin-susceptible pneumococci (MIC90: 1-2 μg/mL), Haemophilus influenzae (MIC90: 0.25-0.5 μg/mL), Moraxella catarrhalis (MIC90: 0.5 μg/mL), and most nonenteric Gram-negative bacilli (MIC90: 2-4 μg/mL).
For research use only. We do not sell to patients.
- Purity: 98.31%
- CAS No.: 143488-32-8
- Formula: C41H41FN10O12S2
- Molecular Weight:948.95
-
Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
Chemical Information
-
CAS No. 143488-32-8
-
Appearance Solid
-
Molecular Weight 948.95
-
Formula C41H41FN10O12S2
-
Color White to off-white
-
SMILES
OC(C1=C(CN2CCN(C(C=C3N(C4CC4)C=C5C(O)=O)=C(F)C=C3C5=O)CC2)CS[C@@]([C@@H]6NC(/C(C7=CSC(N)=N7)=N\OC(C)(C)C(NNC(C8=CC(O)=C(C=C8)O)=O)=O)=O)([H])N1C6=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (105.38 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0538 mL | 5.2690 mL | 10.5380 mL | 26.3449 mL |
| 5 mM | 0.2108 mL | 1.0538 mL | 2.1076 mL | 5.2690 mL | |
| 10 mM | 0.1054 mL | 0.5269 mL | 1.0538 mL | 2.6345 mL | |
| 15 mM | 0.0703 mL | 0.3513 mL | 0.7025 mL | 1.7563 mL | |
| 20 mM | 0.0527 mL | 0.2634 mL | 0.5269 mL | 1.3172 mL | |
| 25 mM | 0.0422 mL | 0.2108 mL | 0.4215 mL | 1.0538 mL | |
| 30 mM | 0.0351 mL | 0.1756 mL | 0.3513 mL | 0.8782 mL | |
| 40 mM | 0.0263 mL | 0.1317 mL | 0.2634 mL | 0.6586 mL | |
| 50 mM | 0.0211 mL | 0.1054 mL | 0.2108 mL | 0.5269 mL | |
| 60 mM | 0.0176 mL | 0.0878 mL | 0.1756 mL | 0.4391 mL | |
| 80 mM | 0.0132 mL | 0.0659 mL | 0.1317 mL | 0.3293 mL | |
| 100 mM | 0.0105 mL | 0.0527 mL | 0.1054 mL | 0.2634 mL |