Ro 31-6840
Ro 31-6840 is an active compound.
For research use only. We do not sell to patients.
- CAS No.: 119555-47-4
- Formula: C9H12FN3O3
- Molecular Weight:229.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| C8166 | IC50 |
0.7 μM
Compound: 12
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Antiviral activity against HIV-1 (RF strain) in C8166 cells
Antiviral activity against HIV-1 (RF strain) in C8166 cells
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[PMID: 2165161] |
| CCRF-CEM | EC50 |
1.1 μM
Compound: 10a
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Effect on HIV-induced cytopathogenesis in CEM cells.
Effect on HIV-induced cytopathogenesis in CEM cells.
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[PMID: 1351945] |
| CCRF-CEM | IC50 |
>100 μM
Compound: 13
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Cytotoxicity in CEM cells
Cytotoxicity in CEM cells
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10.1016/0960-894X(95)00133-E |
| CCRF-CEM | IC50 |
43 μM
Compound: 10a
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Effect on HIV-induced cytopathogenesis in CEM cells.
Effect on HIV-induced cytopathogenesis in CEM cells.
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[PMID: 1351945] |
| HepG2 2.2.15 | EC50 |
4 μM
Compound: 13
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In vitro anti-HBV activity in 2.2.15 cells
In vitro anti-HBV activity in 2.2.15 cells
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10.1016/0960-894X(95)00133-E |
| HepG2 2.2.15 | IC50 |
>200 μM
Compound: 13
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Cytotoxicity in 2.2.15 cells
Cytotoxicity in 2.2.15 cells
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10.1016/0960-894X(95)00133-E |
| HL-60 | IC50 |
707 μM
Compound: 12
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Cytotoxicity was tested in HL60 cells by the trypan blue exclusion assay.
Cytotoxicity was tested in HL60 cells by the trypan blue exclusion assay.
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[PMID: 1695683] |
| MT4 | EC50 |
2.54 μM
Compound: 12
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AntiHIV-1 activity measured in MT-4 cells at 5 to 6 different concentrations, using the reverse transcriptase (RT) assay
AntiHIV-1 activity measured in MT-4 cells at 5 to 6 different concentrations, using the reverse transcriptase (RT) assay
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[PMID: 1695683] |
| MT4 | EC50 |
2.66 μM
Compound: 12
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AntiHIV-1 activity measured in MT-4 cells at 5 to 6 different concentrations, using the P24 antigen enzyme-linked immunosorbent assay (ELISA).
AntiHIV-1 activity measured in MT-4 cells at 5 to 6 different concentrations, using the P24 antigen enzyme-linked immunosorbent assay (ELISA).
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[PMID: 1695683] |
| MT4 | ED50 |
9.8 μM
Compound: 14b
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Inhibitory activity against HIV-1 replication in MT-4 cells
Inhibitory activity against HIV-1 replication in MT-4 cells
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[PMID: 2754700] |
| MT4 | IC50 |
872 μM
Compound: 12
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Cytotoxicity was tested in MT-4 cells by the XTT-microculture tetrazolium assay.
Cytotoxicity was tested in MT-4 cells by the XTT-microculture tetrazolium assay.
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[PMID: 1695683] |
| Vero | IC50 |
>100 μM
Compound: 13
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Cytotoxicity in Vero cells
Cytotoxicity in Vero cells
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10.1016/0960-894X(95)00133-E |
Chemical Information
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CAS No. 119555-47-4
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Molecular Weight 229.21
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Formula C9H12FN3O3
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SMILES
OC[C@@H]1C[C@H](F)[C@H](N2C=CC(N)=NC2=O)O1
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Synonyms
2'βFddC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ro 31-6840 Related Classifications
HY-W995229 Related Classifications
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