Roseorubicin A
Roseorubicin A has anti-Gram-positive bacteria and mycobacterium effect. Roseorubicin A also inhibits leukaemia L1210 with an IC50 of 0.04 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 70559-00-1
- Formula: C54H78N2O18
- Molecular Weight:1043.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 70559-00-1
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Molecular Weight 1043.20
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Formula C54H78N2O18
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SMILES
O=C1C2=C(C(O)=CC=C2)C(C3=C1C(O)=C4C(O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@@H]([C@@H](O7)C)O[C@H]8CC[C@@H]([C@@H](O8)C)O[C@H]9C[C@@H](C[C@@H](O9)C)O)O)N(C)C)N(C)C)[C@@](O)(CC)CCC4=C3O)=O
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Structure Classification
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Initial Source
Actinomyces roseoviolaceus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Roseorubicin A Related Classifications
HY-N14572 Related Classifications
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