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Cat. No.: HY-15035R

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S-Diclofenac (Standard)

(Synonyms: ACS 15 (Standard); ATB-337 (Standard))

S-Diclofenac (Standard) is the analytical standard of S-Diclofenac. This product is intended for research and analytical applications. S-Diclofenac (ACS 15) is a hybrid molecule of an H2S donor and the NSAID diclofenac. S-Diclofenac activates the p53 signaling pathway, and inhibits the activation of JNK. S-Diclofenac exhibits antioxidant and anti-inflammatory activities.

For research use only. We do not sell to patients.

CAS No.: 912758-00-0
Formula: C₂₃H₁₅Cl₂NO₂S₃
Molecular Weight:504.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

S-Diclofenac (Standard) Chemical Structure

CAS No.: 912758-00-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information
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Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 912758-00-0
Molecular Weight 504.47
Formula C₂₃H₁₅Cl₂NO₂S₃
SMILES

O=C(CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1)OC3=CC=C(C(SS4)=CC4=S)C=C3
Synonyms

ACS 15 (Standard); ATB-337 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Wallace JL, et al. Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat. Gastroenterology. 2007 Jan;132(1):261-71. [Content Brief]

[2]. Sidhapuriwala J, et al., Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative, on carrageenan-induced hindpaw oedema formation in the rat. Eur J Pharmacol. 2007 Aug 13;569(1-2):149-54. [Content Brief]

[3]. Zhang H, et al., S-diclofenac protects against doxorubicin-induced cardiomyopathy in mice via ameliorating cardiac gap junction remodeling. PLoS One. 2011;6(10):e26441 [Content Brief]

[4]. Baskar R, et al., Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation. Eur J Pharmacol. 2008 Oct 10;594(1-3):1-8. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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