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Cat. No.: HY-122783A

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(S)-Isogambogic acid

(S)-Isogambogic acid is a caged xanthone isolated from the resin of Garcinia hanburyi that exhibits cytotoxic activity. (S)-Isogambogic acid serves as a detection marker for the quality control of Garcinia hanburyi.

For research use only. We do not sell to patients.

CAS No.: 942623-57-6
Formula: C₃₈H₄₄O₈
Molecular Weight:628.75

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(S)-Isogambogic acid Chemical Structure

CAS No.: 942623-57-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

(S)-Isogambogic acid (E43) is detected in dried resin powder, with a retention time of 19.8 min, a mass-to-charge ratio of m/z 627 for [M-H]⁻, and a mass-to-charge ratio of m/z 629 for [M+H]⁺^[1].
The content of (S)-Isogambogic acid varies among gamboge resin samples from different sources, ranging from 1.76 to 2.50 mg/100 mg crude material^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 942623-57-6
Molecular Weight 628.75
Formula C₃₈H₄₄O₈
SMILES

OC(/C(C)=C/C[C@@]12[C@]34C(C(C5=C(O)C(C=C[C@@](C)(O6)CC/C=C(C)/C)=C6C(C/C=C(C)\C)=C5O3)=O)=C[C@@](C[C@@]4([H])C(C)(O2)C)([H])C1=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yang J, et al. Rapid characterization of caged xanthones in the resin of Garcinia hanburyi using multiple mass spectrometric scanning modes: the importance of biosynthetic knowledge based prediction. Journal of pharmaceutical and biomedical analysis. 2012 Feb 23;60:71-9.

[2]. Li SL, et al. Improved high-performance liquid chromatographic method for simultaneous determination of 12 cytotoxic caged xanthones in gamboges, a potential anticancer resin from Garcinia hanburyi. Biomedical chromatography : BMC. 2008 Jun;22(6):637-44. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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