1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. (S,R,S)-AHPC-PEG3-propionic acid

(S,R,S)-AHPC-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.

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(S,R,S)-AHPC-PEG3-propionic acid

(S,R,S)-AHPC-PEG3-propionic acid Estructura química

No. CAS : 2140807-42-5

Tamaño Precio Stock Cantidad
25 mg Obtener un presupuesto 3 - 4 weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  
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Descripciòn

(S,R,S)-AHPC-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology[1].

IC50 & Target[1]

VHL

 

Peso molecular

662.79

Fòrmula

C32H46N4O9S

No. CAS
Appearance

Liquid (Density: 1.264±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCOCCOCCOCCC(O)=O)=O)=O)C[C@H](O)C3

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Pureza y Documentación
Referencias
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(S,R,S)-AHPC-PEG3-propionic acid Related Classifications

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
(S,R,S)-AHPC-PEG3-propionic acid
Cat. No.:
HY-136165
Cantidad:
MCE Japan Authorized Agent: