S100A2-p53-IN-1
S100A2-p53-IN-1 (compound 51) is a S100A2-p53 interactions inhibitor. S100A2 is a Ca2+ binding protein with implications in cell signaling and is known to be upregulated in pancreatic cancer. S100A2-p53-IN-1 can inhibit the growth of the MiaPaCa-2 pancreatic cancer cell line (GI50 of 1.2-3.4 μM).
For research use only. We do not sell to patients.
- CAS No.: 2766609-08-7
- Formula: C20H20F6N2O4S
- Molecular Weight:498.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | GI50 |
1.5 μM
Compound: 51
|
Growth inhibition of human A2780 cells incubated for 72 hrs by MTT assay
Growth inhibition of human A2780 cells incubated for 72 hrs by MTT assay
|
[PMID: 35114371] |
| ASPC1 | GI50 |
2.9 μM
Compound: 51
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Growth inhibition of human ASPC1 cells incubated for 72 hrs by MTT assay
Growth inhibition of human ASPC1 cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
| BE(2)-C | GI50 |
2.8 μM
Compound: 51
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Growth inhibition of human BE2C cells incubated for 72 hrs by MTT assay
Growth inhibition of human BE2C cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
| BXPC-3 | GI50 |
1.2 μM
Compound: 51
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Growth inhibition of human BXPC-3 cells incubated for 72 hrs by MTT assay
Growth inhibition of human BXPC-3 cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
| Capan-2 | GI50 |
2.5 μM
Compound: 51
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Growth inhibition of human Capan-2 cells incubated for 72 hrs by MTT assay
Growth inhibition of human Capan-2 cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
| HPAC | GI50 |
2.7 μM
Compound: 51
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Growth inhibition of human HPAC cells incubated for 72 hrs by MTT assay
Growth inhibition of human HPAC cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
| HT-29 | GI50 |
2.2 μM
Compound: 51
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Growth inhibition of human HT-29 cells incubated for 72 hrs by MTT assay
Growth inhibition of human HT-29 cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
| MCF-10A | GI50 |
3.2 μM
Compound: 51
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Growth inhibition of human MCF-10A cells incubated for 72 hrs by MTT assay
Growth inhibition of human MCF-10A cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
| MCF7 | GI50 |
2.5 μM
Compound: 51
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Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
| MIA PaCa-2 | GI50 |
2.6 μM
Compound: 51
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Growth inhibition of human MIA PaCa-2 cells incubated for 72 hrs by MTT assay
Growth inhibition of human MIA PaCa-2 cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
| PANC-1 | GI50 |
3.4 μM
Compound: 51
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Growth inhibition of human PANC-1 cells incubated for 72 hrs by MTT assay
Growth inhibition of human PANC-1 cells incubated for 72 hrs by MTT assay
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[PMID: 35114371] |
Chemical Information
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CAS No. 2766609-08-7
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Molecular Weight 498.44
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Formula C20H20F6N2O4S
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SMILES
O=S(NCCCNCC1COC2=C(O1)C=CC=C2)(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
S100A2-p53-IN-1 Related Classifications
HY-145900 Related Classifications
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