Saponin C, from Liriope muscari
Based on 1 Customer Validation
Saponin C, from Liriope muscari is isolated from Liriope muscari.
For research use only. We do not sell to patients.
- Purity : 99.83%
- CAS No.: 130551-41-6
- Formula: C44H70O17
- Molecular Weight:871.02
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Description
Chemical Information
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CAS No. 130551-41-6
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Appearance Solid
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Molecular Weight 871.02
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Formula C44H70O17
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Color White to yellow
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SMILES
C[C@@]12[C@]3([H])[C@](O[C@]4(CC[C@@H](C)CO4)[C@H]3C)([H])C[C@@]1([H])[C@@]5([H])[C@]([C@]6([C@@H](C[C@H](O)CC6=CC5)O[C@@]7([H])[C@@H]([C@H]([C@@H](O)[C@@H](C)O7)O[C@@]8([H])[C@@H]([C@H]([C@H](O)CO8)O)O)O[C@]9([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]9O)CO)C)([H])CC2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (114.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (2.87 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (248 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1481 mL | 5.7404 mL | 11.4808 mL | 28.7020 mL |
| 5 mM | 0.2296 mL | 1.1481 mL | 2.2962 mL | 5.7404 mL | |
| 10 mM | 0.1148 mL | 0.5740 mL | 1.1481 mL | 2.8702 mL | |
| 15 mM | 0.0765 mL | 0.3827 mL | 0.7654 mL | 1.9135 mL | |
| 20 mM | 0.0574 mL | 0.2870 mL | 0.5740 mL | 1.4351 mL | |
| 25 mM | 0.0459 mL | 0.2296 mL | 0.4592 mL | 1.1481 mL | |
| 30 mM | 0.0383 mL | 0.1913 mL | 0.3827 mL | 0.9567 mL | |
| 40 mM | 0.0287 mL | 0.1435 mL | 0.2870 mL | 0.7175 mL | |
| 50 mM | 0.0230 mL | 0.1148 mL | 0.2296 mL | 0.5740 mL | |
| 60 mM | 0.0191 mL | 0.0957 mL | 0.1913 mL | 0.4784 mL | |
| 80 mM | 0.0144 mL | 0.0718 mL | 0.1435 mL | 0.3588 mL | |
| 100 mM | 0.0115 mL | 0.0574 mL | 0.1148 mL | 0.2870 mL |