2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor Dopamine Receptor
  4. Sarizotan dihydrochloride

Sarizotan dihydrochloride  (Synonyms: EMD 128130 dihydrochloride)

Cat. No.: HY-100820B
Instruction de manipulation Technical Support

Sarizotan dihydrochloride (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively.

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Sarizotan dihydrochloride

Sarizotan dihydrochloride Chemical Structure

CAS No. : 177976-12-4

Size Prix Stock Quantité
1 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
5 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
10 mg Obtenir un devis 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
50 mg   Obtenir un devis  
100 mg   Obtenir un devis  
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Based on 1 publication(s) in Google Scholar

Other Forms of Sarizotan dihydrochloride:

Sarizotan dihydrochloride Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Sarizotan dihydrochloride

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5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

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Description

Sarizotan dihydrochloride (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively[1].

IC50 & Target

5-HT1A Receptor

0.1 nM (IC50)

5-HT1A Receptor

 

Human D3 Receptor

6.8 nM (IC50)

5-HT2A Receptor

587 nM (IC50)

5-HT2B Receptor

108 nM (IC50)

5-HT5A Receptor

313 nM (IC50)

Human 5-HT6 Receptor

3300 nM (IC50)

Human 5-HT7 Receptor

10 nM (IC50)

Masse moléculaire

421.34

Formule

C22H23Cl2FN2O
CAS No.
SMILES

FC(C=C1)=CC=C1C2=CN=CC(CNC[C@@H]3OC4=CC=CC=C4CC3)=C2.Cl.Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Sarizotan dihydrochloride Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sarizotan177976-12-4EMD 128130EMD128130EMD-1281305-HT ReceptorDopamine ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorParkinson’sdiseaseDOPAdyskinesiaInhibitorinhibitorinhibit

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