177976-12-4
177976-12-4
Chemical Structure
Sarizotan dihydrochloride
Synonym(s): EMD 128130 dihydrochloride
- CAS No.: 177976-12-4
- Formula:C22H23Cl2FN2O
- Molecular Weight:421.34
InChIKey: ANXOJXYTTDGHAJ-GHVWMZMZSA-N
SMILES: FC(C=C1)=CC=C1C2=CN=CC(CNC[C@@H]3OC4=CC=CC=C4CC3)=C2.Cl.Cl
Biological Activity: Sarizotan dihydrochloride (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sarizotan dihydrochloride | Sarizotan dihydrochloride (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively. | |||||||||||||||||||||
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