1. Anti-infection
  2. SARS-CoV
  3. SARS-CoV-2-IN-24

SARS-CoV-2-IN-24 

Cat. No.: HY-150783
Handling Instructions

SARS-CoV-2-IN-24 (compound 7) is a potent papain-like protease (PLpro) inhibitor. SARS-CoV-2-IN-24 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. SARS-CoV-2-IN-24 can be used for SARS-CoV-2 research.

For research use only. We do not sell to patients.

SARS-CoV-2-IN-24 Chemical Structure

SARS-CoV-2-IN-24 Chemical Structure

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Description

SARS-CoV-2-IN-24 (compound 7) is a potent papain-like protease (PLpro) inhibitor. SARS-CoV-2-IN-24 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. SARS-CoV-2-IN-24 can be used for SARS-CoV-2 research[1].

In Vitro

SARS-CoV-2-IN-24 (compound 7) induces conformational changes manly in BL2’ region and increases the activity against PLpro[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

490.55

Formula

C27H30N4O5

SMILES

COC(/C=C/C(NNC(CCC1=CC=C(C=C1C(N[[email protected]@H](C2=C3C=CC=CC3=CCC2)C)=O)N)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2

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Product Name:
SARS-CoV-2-IN-24
Cat. No.:
HY-150783
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