1. Anti-infection
  2. SARS-CoV
  3. SARS-CoV-2-IN-35

SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a Ki value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19.

For research use only. We do not sell to patients.

SARS-CoV-2-IN-35 Chemical Structure

SARS-CoV-2-IN-35 Chemical Structure

CAS No. : 2757763-47-4

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Description

SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a Ki value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19[1].

In Vivo

SARS-CoV-2-IN-35 (compound 5; 10 mg/kg; p.o.) has good oral utilization in Wistar-Han rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar-Han rats[1]
Dosage: 10 mg/kg
Administration: Oral administration
Result: Had oral F of 33 %.
Molecular Weight

621.67

Formula

C29H34F3N5O5S

CAS No.
SMILES

O=C(C1=NC2=CC=CC=C2S1)[C@H](C[C@H]3C(NCC3)=O)NC([C@@H]4[C@]5([H])[C@@](CN4C([C@H](C(C)C)NC(C(F)(F)F)=O)=O)([H])C5(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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SARS-CoV-2-IN-35 Related Classifications

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  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SARS-CoV-2-IN-35
Cat. No.:
HY-148387
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