SARS-CoV-2-IN-55
SARS-CoV-2-IN-55(compound 65) is a low cytotoxicity inhibtor of SARS-CoV-2 with an IC50 value of 0.3 μM, by the direct interaction with VSV-S pseudoparticles.
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- Fòrmula: C138H136N22O32S6
- Peso molecular:2807.07
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
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Help & FAQs
Actividad biológica
IC50: 0.3 μM (SARS-CoV-2)[1]
SARS-CoV-2-IN-55 (10 μM, 24 h) inhibits the viral activity of SARS-CoV-2 in Vero E6 cell and A549-ACE2-TMPRSS2 cell respectively with the IC50 value of 0.3 μM and 15.8 μM, meanwhile inhibits the viral activity of Wuhan-Hu-1 (IC50=0.28 μM) and Omicron BA.1 (IC50=6.24 μM) in Vero E6-TMPRSS2 cell[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Vero E6 , A549-Ace2-TMPRSS2 cell, Vero E6-TMPRSS2 Cell [1]
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Concentration:10 μM
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Incubation Time:24 h
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Result:Inhibted the viral activity of SARS-CoV-2 in Vero E6 and A549-Ace2-TMPRSS2 cell.
Inhibted the viral activity of Wuhan-Hu-1 and Omicron BA.1 in Vero E6-TMPRSS2 Cell.
Chemical Information
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Peso molecular 2807.07
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Fòrmula C138H136N22O32S6
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SMILES
O=C(NC(CC1=C(SC2=CC=C(C=C2)[N+]([O-])=O)NC3=CC=CC=C31)C=O)CCC(CCC(NC(C=O)CC4=C(NC5=C4C=CC=C5)SC6=CC=C(C=C6)[N+]([O-])=O)=O)(NC(CNC(CCOCCOCCOCCOCCC(NCC(NC(CCC(NC(C=O)CC7=C(NC8=C7C=CC=C8)SC9=CC=C(C=C9)[N+]([O-])=O)=O)(CCC(NC(C=O)CC%10=C(NC%11=C%10C=CC=C%11)SC%12=CC=C(C=C%12)[N+]([O-])=O)=O)CCC(NC(CC%13=C(NC%14=C%13C=CC=C%14)SC%15=CC=C(C=C%15)[N+]([O-])=O)C=O)=O)=O)=O)=O)=O)CCC(NC(CC%16=C(NC%17=C%16C=CC=C%17)SC%18=CC=C(C=C%18)[N+]([O-])=O)C=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SARS-CoV-2-IN-55 Related Classifications
HY-155734 Related Classifications
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