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Cat. No.: HY-163067

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SARS-CoV-2-IN-71

SARS-CoV-2-IN-71 (compound 8h) is a potent inhibitor of SARS-CoV-2. SARS-CoV-2-IN-71 inhibits coronavirus replication at multiple stages. SARS-CoV-2-IN-71 displays anti-coronaviral effect by simultaneously acting on 3CL^pro and TMPRSS2.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₃H₂₄F₆N₄O₄
분자량:534.45

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

SARS-CoV-2-IN-71 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
A549	CC₅₀	>100 μM Compound: 8h	Cytotoxicity against human A549 cells incubated for 72 hrs by CCK-8 assay Cytotoxicity against human A549 cells incubated for 72 hrs by CCK-8 assay	[PMID: 38061229]
Huh-7	CC₅₀	>50 μM Compound: 8h	Cytotoxicity against human Huh-7 cells incubated for 72 hrs by CCK-8 assay Cytotoxicity against human Huh-7 cells incubated for 72 hrs by CCK-8 assay	[PMID: 38061229]
Huh-7.5	CC₅₀	>50 μM Compound: 8h	Cytotoxicity against human Huh7.5 cells incubated for 72 hrs by CCK-8 assay Cytotoxicity against human Huh7.5 cells incubated for 72 hrs by CCK-8 assay	[PMID: 38061229]
NCI-H460	CC₅₀	67.03 μM Compound: 8h	Cytotoxicity against human NCI-H460 cells incubated for 72 hrs by CCK-8 assay Cytotoxicity against human NCI-H460 cells incubated for 72 hrs by CCK-8 assay	[PMID: 38061229]

Chemical Information

분자량 534.45
화학식 C₂₃H₂₄F₆N₄O₄
SMILES

O=C(NC1=CC=C(C(C(F)(F)F)=C1)CN2CC(C2)N(C)C)C(C=C3[N+]([O-])=O)=CC=C3OCCC(F)(F)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li J, et al. Design, synthesis and biological evaluation of biaryl amide derivatives against SARS-CoV-2 with dual-target mechanism. Eur J Med Chem. 2023 Nov 25;264:115978. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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