SB1617
SB1617 is a neuroinflammation-modulating agent, and has neuroprotective effect by reducing pathogenic tau levels through microglia-mediated anti-inflammatory activity.
For research use only. We do not sell to patients.
- Formula: C22H21ClN6O5S
- Molecular Weight:516.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 516.96
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Formula C22H21ClN6O5S
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SMILES
ClC1=CC=C(CN(C2=NN=CC3=C2[C@@H](OC4)N(S(C5=CC=C([N+]([O-])=O)C=C5)(=O)=O)[C@H]4CN3)C)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Cho H, et al. Neuroinflammation-Modulating Agent SB1617 Enhances LC3-Associated Phagocytosis to Mitigate Tau Pathology. ACS Chem Neurosci. 2023;14(23):4139-4152. [Content Brief]
[2]. Shin YH, et al. Phenotypic Discovery of Neuroprotective Agents by Regulation of Tau Proteostasis via Stress-Responsive Activation of PERK Signaling. Angew Chem Int Ed Engl. 2021;60(4):1831-1838. doi:10.1002/anie.202013915 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SB1617 Related Classifications
HY-162020 Related Classifications
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