IAN-15B
IAN-15B has high selectivity and potent ST6GAL1 inhibitors (IC50 = 3.3 μM). IAN-15B has significant anti migratory and anti angiogenic effects. IAN-15B can be used in the research of cancer such as breast cancer.
For research use only. We do not sell to patients.
- Formula: C44H55N9O4
- Molecular Weight:773.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 773.97
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Formula C44H55N9O4
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SMILES
[H][C@]12CC[C@@]3([C@H](CC[C@]3([C@@]1(CC[C@@]4(C[C@@H](CC[C@]24C)O)[H])[H])[H])[C@@H](CCC(N[C@@H](C(O)=O)CC(C5=CNC6=C5C=C(C=C6)N=[N+]=[N-])C7=CNC8=C7C=C(C=C8)N=[N+]=[N-])=O)C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)