218 Results for "

2-Pentylcyclohexanone

" in MedChemExpress (MCE) Product Catalog:
Products (218)

218 Results for "2-Pentylcyclohexanone" in MCE Product Catalog:

Cat. No.: HY-P11892
c10c-G1V3 is a BRAG2 binder with a Kd value of 7.37 μM. c10c-G1V3 binds to BRAG2, thereby disrupting its interaction with GluA2 and blocking GluA2 endocytosis and AMPAR subunit switching. c10c-G1V3 reduces glutamate-induced intracellular reactive oxygen species (ROS) accumulation and cell apoptosis (apoptosis). c10c-G1V3 decreases infarct volume in the transient middle cerebral artery occlusion model. c10c-G1V3 can be used in studies related to ischemic stroke .
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Cat. No.: HY-P11894
Target:  

Bacterial

Research Areas:  

Infection

Antimicrobial peptide 6b is a cationic macrocyclic antimicrobial peptide. It exhibits broad-spectrum antibacterial and antifungal activities, with a MIC of 1.5-6.2 μg/mL against drug-resistant Gram-positive bacteria, a MIC of 4-25 μg/mL against Gram-negative bacteria, and also shows activity against pathogenic fungi. It acts through a membrane disruption mechanism, has a unique "sandwich" conformation, low hemolytic activity, and can rapidly kill bacteria and eliminate bacterial and fungal biofilms. Antimicrobial peptide 6b can be used in studies of drug-resistant bacterial infections and fungal infections .
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Cat. No.: HY-P11895
CAS No.: 3081054-21-6
Research Areas:  

Neurological Disease

Tyr-c [D-Lys-p-F-Phe-Phe-Asp]-D-Pro-NH2 is a multi-opioid receptor (Opioid Receptor) modulator, acting as a MOR/KOR agonist and a DOR antagonist. Tyr-c [D-Lys-p-F-Phe-Phe-Asp]-D-Pro-NH2 activates the G protein-mediated cAMP inhibitory pathway and β-arrestin2 recruitment pathway downstream of MOR, with an EC50 of 159 nM for β-arrestin2 recruitment, an EC50 of 1.1 nM for MOR-mediated calcium mobilization, and an EC50 of 397 nM for KOR. Tyr-c [D-Lys-p-F-Phe-Phe-Asp]-D-Pro-NH2 exhibits potent analgesic activity in vivo. It can be used in studies related to opioid receptor function and analgesia .
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Cat. No.: HY-P11896
CAS No.: 3081054-30-7
Research Areas:  

Neurological Disease

Tyr-c[D-Lys-p-Br-Phe-Phe-Asp]-D-Pro-NH2 is a MOR-selective antagonist with a pA2 value of 9.9. Tyr-c[D-Lys-p-Br-Phe-Phe-Asp]-D-Pro-NH2 blocks G protein- and β-arrestin2-mediated downstream signaling pathways of MOR. Tyr-c[D-Lys-p-Br-Phe-Phe-Asp]-D-Pro-NH2 significantly delays the development of μ-opioid agonist-induced analgesic tolerance by blocking peripheral MOR. Tyr-c[D-Lys-p-Br-Phe-Phe-Asp]-D-Pro-NH2 is applicable to studies related to opioid receptor function and analgesic tolerance .
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Cat. No.: HY-P6176
CAS No.: 3032608-72-0
Target:  

Melanocortin Receptor

Research Areas:  

Metabolic Disease Endocrinology

JLB2-110c activates MCRs receptor (mMC4R EC50 = 0.34 nM) and has a strong in vivo appetite suppressant effect .
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Cat. No.: HY-175323
Target:  

Integrin PD-1/PD-L1

Research Areas:  

Cancer

NOTA-IMB-RGD is a dual molecular probe targeting integrin αvβ3 and programmed death ligand-1 (PD-L1). NOTA-IMB-RGD blocks the PD-1/PD-L1 signaling pathway and integrin αvβ3-overexpressing tumor vasculature. NOTA-IMB-RGD is promising for research of solid tumors co-expressing PD-L1 and αvβ3 (e.g., glioma, breast cancer) .
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Cat. No.: HY-P10649
CAS No.: 1831064-62-0
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

CPP12 is a small, amphipathic, cyclic cell-penetrating peptide (CPP). CPP12 binds directly to plasma membrane phospholipids, enters mammalian cells via endocytosis, and then efficiently escapes from endosomes. CPP12 can be used for the intracellular delivery of drugs and chemical probes .
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Cat. No.: HY-P10649A
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

CPP12 TFA is a small, amphipathic, cyclic cell-penetrating peptide (CPP). CPP12 TFA binds directly to plasma membrane phospholipids, enters mammalian cells via endocytosis, and then efficiently escapes from endosomes. CPP12 TFA can be used for the intracellular delivery of drugs and chemical probes .
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Cat. No.: HY-P11622
CAS No.: 3106317-27-2
Target:  

Drug Derivative

Research Areas:  

Infection

Gramicidin S analogue 9 is a bactericidal agent that can be found as a cyclic peptide analogue. Gramicidin S analogue 9 disrupts bacterial cell membranes. Gramicidin S analogue 9 can be used for the research of methicillin-resistant staphylococcus aureus infection .
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Cat. No.: HY-P11783
CAS No.: 86711-55-9
Target:  

Fungal

Research Areas:  

Infection

Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .
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Cat. No.: HY-P1674
CAS No.: 944252-63-5
Synonyms: POL7080
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Murepavadin (POL7080), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with both MIC50 and MIC90 values of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance [2].
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Cat. No.: HY-P2005
CAS No.: 59926-78-2
Malformin C is an algicidal peptide can be isolated from Aspergillus and exhibits dose-dependent algicidal activity. Malformin C induces a significant increase in ROS levels in algal cells, resulting in impaired SOD activity and high production of MDA content .
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Cat. No.: HY-P3987A
Target:  

Sec61

Research Areas:  

Cancer

Cotransin TFA is a cyclic ester peptide and a Sec61 translocator binder with signal sequence-selective activity to inhibit co-translational protein translocation. Cotransin TFA inhibits the biogenesis of a subset of secretory and membrane proteins in a signal peptide-dependent manner. Cotransin TFA is applicable for cancer-related research [2].
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Cat. No.: HY-P10819
Research Areas:  

Cancer

S9-CMC1 TFA is a covalent peptide lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 value of 2.53 μM. S9-CMC1 TFA specifically recognizes Cys360 in the enzyme-active region. S9-CMC1 TFA inhibits LSD1 activity, increasing H3K4me1 and H3K4me2 levels, leading to G1 cell cycle arrest and apoptosis and inhibiting cell proliferation. S9-CMC1 TFA significantly inhibits tumor growth in A549 xenograft animal models .
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Cat. No.: HY-P10978
CAS No.: 3137461-57-2
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

NK224 is a peptide-based radiotracer targeting human PD-L1, with dual-radionuclide (68Ga and 18F) labeling compatibility enabled by the NOTA chelator. NK224 exhibits high binding affinity to PD-L1, with an IC50 value of 2.45 nM. NK224 visualizes tumor heterogeneity and dynamically monitors PD-L1 target occupancy during immunotherapy. NK224 can be used for the study of non-small cell lung cancer (NSCLC) .
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Cat. No.: HY-P2274
CAS No.: 243975-37-3
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .
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Cat. No.: HY-P2596
CAS No.: 115295-08-4
Target:  

Inhibitory Antibodies

Research Areas:  

Others

BC 197 is an active compound.
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Cat. No.: HY-P10442
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Cinnamosyn is a 10-mer N-cinnamoyl-containing peptide that is cytotoxic to human cells .
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Cat. No.: HY-P10785
CAS No.: 83785-07-3
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Iturin A-2 is a cyclic lipopeptide discovered in B. subtilis and exhibits inhibitory activity against the plant pathogenic fungus P. expansum (MIC = 8 µg/disk). Iturin A-2 is cytotoxic to MCF-7 and BT474 breast cancer cells, as well as HeLa cervical cancer cells, with IC50 values of 66.81, 95.04, and 77.5 µg/mL, respectively. In greenhouse studies, Iturin A-2 at concentrations of 100 and 300 mg/kg Iturin A-2 reduces the lesion area of southern corn leaf blight caused by B. maydis, and in field studies, concentrations of 300 and 500 mg/kg Iturin A-2 reduce the incidence of the disease. Iturin A-2 (12.5 µg/mL) inhibits cell division, but not nuclear division, in isolated fertilized starfish eggs [2] .
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Cat. No.: HY-P10888
CAS No.: 3066113-41-2
Target:  

Glycoprotein VI

Research Areas:  

Cancer

GPC3 targeting peptide 1 is a GPC3 targeting peptide, with a Kd value of 0.23 nM [2].
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