2347 Results for "

component

" in MedChemExpress (MCE) Product Catalog:
Products (2347)

2347 Results for "component" in MCE Product Catalog:

Cat. No.: HY-184579
Research Areas:  

Others

DMG-PEG1000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. DMG-PEG1000-cRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against αvβ3/αvβ5 integrins on tumor vasculature and cancer cell surfaces.
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Cat. No.: HY-184579A
Research Areas:  

Others

DMG-PEG2000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. DMG-PEG2000-cRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against αvβ3/αvβ5 integrins on tumor vasculature and cancer cell surfaces.
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Cat. No.: HY-184579B
Research Areas:  

Others

DMG-PEG3400-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 3400 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. DMG-PEG3400-cRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against αvβ3/αvβ5 integrins on tumor vasculature and cancer cell surfaces.
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Cat. No.: HY-184579C
Research Areas:  

Others

DMG-PEG5000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 5000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. DMG-PEG5000-cRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against αvβ3/αvβ5 integrins on tumor vasculature and cancer cell surfaces.
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Cat. No.: HY-187237A
Research Areas:  

Others

DPPE-PEG2000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. DPPE-PEG2000-cRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against αvβ3/αvβ5 integrins on tumor vasculature and cancer cell surfaces.
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Cat. No.: HY-187244A
Research Areas:  

Others

DSG-PEG2000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: distearoylglycerol (DSG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. DSG-PEG2000-cRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against αvβ3/αvβ5 integrins on tumor vasculature and cancer cell surfaces.
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Cat. No.: HY-187744A
Synonyms: DPPE-PEG2000-Mal-Cys-NYZL1
Research Areas:  

Cancer

DPPE-PEG2000-NYZL1 (DPPE-PEG2000-Mal-Cys-NYZL1) is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dispalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and the NYZL1 peptide as a terminal targeting/functional ligand. DPPE-PEG2000-NYZL1 can be used in research on targeted drug delivery for bladder cancer, among other applications .
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Cat. No.: HY-187746A
Synonyms: DPPE-PEG2000-Mal-Cys-ATWLPPR
Research Areas:  

Cancer

DPPE-PEG2000-A7R (DPPE-PEG2000-Mal-Cys-ATWLPPR) is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dispalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and an A7R (HY-P1663) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-A7R can be used in research on tumor angiogenesis-targeted drug delivery, among other applications .
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Cat. No.: HY-187752A
Synonyms: DPPE-PEG2000-Mal-Cys-WEAALAEALAEALAEHLAEALAEALEALAA
Research Areas:  

Others

DPPE-PEG2000-GALA (DPPE-PEG2000-Mal-Cys-WEAALAEALAEALAEHLAEALAEALEALAA) is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a GALA (HY-P5423) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-GALA can be used for pH-responsive drug delivery, endosome escape and cytoplasmic drug release, and cytoplasmic delivery of nucleic acids (siRNA/mRNA) .
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Cat. No.: HY-187785A
Synonyms: DPPE-PEG2000-Mal-Cys-SP94
Research Areas:  

Cancer

DPPE-PEG2000-SP94 (DPPE-PEG2000-Mal-Cys-SP94) is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and an SP94 (HY-P11050A) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-SP94 can be used in research on targeted drug delivery for hepatocellular carcinoma .
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Cat. No.: HY-187809A
Synonyms: DPPE-PEG2000-Mal-Cys-THRPPMWSPVWP
Research Areas:  

Cancer

DPPE-PEG2000-THRPPMWSPVWP (DPPE-PEG2000-Mal-Cys-THRPPMWSPVWP) is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphoethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a TfR-T12 (THRPPMWSPVWP) (HY-P2297) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-THRPPMWSPVWP can be used for brain-targeted drug delivery and the construction of drug delivery systems for central nervous system diseases .
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Cat. No.: HY-B0152S2
Synonyms: 6-Aminopurine-13C5,15N5; Vitamin B4-13C5,15N5
Adenine- 13C5,15C5 (6-Aminopurine- 13C5,15C5; Vitamin B4- 13C5,15C5) is 13C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
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Cat. No.: HY-B2176S4
Synonyms: Adenosine 5'-triphosphate-d14 dilithium
ATP-d14 (Adenosine 5'-triphosphate-ATP-d14) dilithium is the d14-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice .
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Cat. No.: HY-D3436
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Pt-Luc is a bioluminescent probe used for real-time, non-invasive monitoring of Pt (IV) prodrug reduction in living cells and animal models. The detection mechanism of Pt-Luc relies on the intracellular reduction mediated by active cysteine residues in proteins. Pt-Luc can penetrate the membrane of living cells; after entering cells, active cysteine thiolates in high-molecular-weight protein components reduce the Pt (IV) complex, thereby cleaving the caged aminoluciferin substrate. The released free aminoluciferin is then oxidized by luciferase in the presence of ATP to generate a bioluminescent signal, whose intensity is directly correlated with the reduction degree of Pt (IV) .
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Cat. No.: HY-N0500
CAS No.: 130567-83-8
Mogroside III is a triterpenoid glycoside. Mogroside III exhibits maltase inhibitory effect with an IC50 value of 1.6 mM. Mogroside III enhances oocyte developmental potential by promoting autophagy in cumulus cells. Mogroside III, as the active ingredient of the low-polarity glycoside component (L-SGgly), L-SGgly can increase serum GLP-1 levels, improve insulin resistance, and reduce IL-6 levels, and has hypoglycemic, lipid-regulating and anti-inflammatory effects. Mogroside III can be used for the studies of type 2 diabetes mellitus (T2DM) and assisted reproductive technology .
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Cat. No.: HY-N12851
CAS No.: 2492-43-5
Synonyms: (E)-4-Oxo-2-hexenal
4-OHE ((E)-4-Oxo-2-hexenal) is a mutagen formed by omega-3 lipid peroxidation. 4-OHE reacts with deoxyguanosine, deoxycytidine and 5-methyldeoxycytidine to form covalent adducts. 4-OHE induces apoptosis and exhibits genotoxicity. 4-OHE inhibits the growth of Gram-positive and Gram-negative bacteria, which correlates with its electrophilic reactivity towards nucleophilic biomolecules. 4-OHE is a chemical defense component of Dolycoris baccarum (sloe bug), and acts as a deterrent and toxin against insect predators .
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Cat. No.: HY-P1218B
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Phrixotoxin 3-NH2 TFA is a derivative of Phrixotoxin 3 TFA (HY-P1218A). Phrixotoxin 3 TFA is a potent blocker of voltage-gated sodium channels, with IC50s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively. Phrixotoxin 3 TFA modulates voltage-gated sodium channels with properties similar to those of typical gating-modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current .
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Cat. No.: HY-P1426
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

AmmTX3 is a peptide toxin identified from the venom of the scorpion Androctonus mauretanicus. AmmTX3 is a highly specific blocker of Kv4 channels, which selectively and almost completely blocks transient A-type K + currents with a Ki of 131 nM. AmmTX3 induces epileptiform behaviors and causes death in mice receiving intracerebroventricular injection. AmmTX3 increases the excitability of dentate gyrus granule cells, reduces GABAergic inhibition, enhances and stabilizes the EPSP-spike component of long-term potentiation, and impairs reference memory. AmmTX3 can be used in research related to pain, epilepsy, and autism spectrum disorder .
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Cat. No.: HY-P3160C
CAS No.: 86088-83-7
Fibronectin, bovine plasma is a fibronectin derived from bovine plasma. Fibronectin is an extracellular matrix protein that is upregulated and essential in many developmental processes, and also exists in the pathological progression of tissues and wound healing. Fibronectin specifically binds to a large number of molecules, including other components of the extracellular matrix, signaling molecules and cell adhesion molecules. The interaction between cells and fibronectin leads to bidirectional crosstalk, which regulates cell functions and induces cell-dependent changes in the extracellular matrix. Fibronectin, bovine plasma inhibits the production of bovine leukemia virus (BLV) p24 core protein in naturally infected bovine peripheral blood mononuclear cells .
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Cat. No.: HY-RS16289
Research Areas:  

Cancer

St6galnac4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for St6galnac4 (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
St6galnac4 siRNA-1: 5 nmol (HPLC)
St6galnac4 siRNA-2: 5 nmol (HPLC)
St6galnac4 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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