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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
316 Results for "
PR
" in MedChemExpress (MCE) Product Catalog:
Products (316)
316 Results for "PR" in MCE Product Catalog:
Cat. No.: HY-144668
CAS No.: 3035088-22-0
Target:
Research Areas:
RdRP-IN-4 (compound 11q), an aryl benzoyl hydrazide analog, is an orally active influenza A virus RNA-dependent RNA polymerase (RdRp) inhibitor by interacting with the PB1 subunit. RdRP-IN-4 exhibits potent inhibitory activity against the avian H5N1 flu strain with an EC50 of 18 nM in MDCK cells. RdRP-IN-4 displays excellent potency against the the H1N1 (A/PR/8/34) Flu A strain and Flu B strain (B/Lee/1940) with EC50 values of 53 nM and 20 nM, respectively. RdRP-IN-4 significantly inhibits the expression level of viral nucleoprotein (NP) in a dose-dependent manner. RdRP-IN-4 exhibits significant antiviral activity in infected mice .
Cat. No.: HY-175808
Target:
Research Areas:
VF-57a (Compound 23) is an Influenza A virus (IAV) fusion inhibitor. VF-57 has potent antiviral activities against authentic A/H1N1 virus with EC50s of 0.92 and 0.31 μM for the A/H1N1 PR8 and A/H1N1 Virg09 strains, respectively. VF-57 significantly inhibits HA-mediated cell entry of A/H1N1- and A/H5N1-pseudoviruses, prevents the HA refolding at pH 5.2. VF-57a can be used for IAV infections research .
Cat. No.: HY-P74212
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding PRotein Li 69p; PeptidylPRolyl Isomerase A; PeptidylPRolyl Isomerase A (Cyclophilin A); CYPA; Peptidyl-PRolyl Cis-Trans Isomerase; Peptidyl-PRolyl Cis-Trans Isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding PR
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P71501
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding PRotein Li 69p; PeptidylPRolyl Isomerase A; PeptidylPRolyl Isomerase A (Cyclophilin A); CYPA; Peptidyl-PRolyl Cis-Trans Isomerase; Peptidyl-PRolyl Cis-Trans Isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding PR
Species:
E.coli
Source:
E. coli
Cat. No.: HY-P704051
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Gag polyPRotein; PR55Gag; Matrix PRotein p17; MA; Capsid PRotein p24; CA; Spacer peptide 1; SP1; p2; Nucleocapsid PRotein p7; NC; Spacer peptide 2; SP2
Species:
Virus
Source:
E. coli
Cat. No.: HY-158101R
CAS No.: 2446928-30-7
Synonyms: CC-94676 (Standard)
Research Areas:
BMS-986365 (Standard) is the analytical standard of BMS-986365 (HY-158101). This product is intended for research and analytical applications. BMS-986365 (CC-94676) is an orally active and selective targeted androgen receptor (AR) PROTAC degrader (DC50 of 10-40 nM). BMS-986365 is capable of inducing cereblon (CRBN) E3 ligase-dependent ubiquitination and degradation of the androgen receptor (AR), as well as various AR mutants. BMS-986365 shows no degradation of the close AR family members estrogen receptor (ER), progesterone receptor (PR), and glucocorticoid receptor (GR). BMS-986365 shows significant in vivo potency, degrading AR, inhibiting AR signaling, and restricting tumor growth in animal models of advanced prostate cancer. BMS-986365 can be used for the study of metastatic castration-resistant prostate cancer (mCRPC) .
Cat. No.: HY-P71041
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACAT2; Acetoacetyl Coenzyme A Thiolase; Acetyl-CoA Acetyltransferase 2; Acetyl-Coenzyme A Acetyltransferase 2 (Acetoacetyl Coenzyme A Thiolase); Acetyl-CoA Acetyltransferase, Cytosolic; Acetyl-Coenzyme A Acetyltransferase 2; Acetyl-CoA Transferase-Like PR
Species:
Human
Source:
E. coli
Cat. No.: HY-P75543
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACAT2; Acetoacetyl Coenzyme A Thiolase; Acetyl-CoA Acetyltransferase 2; Acetyl-Coenzyme A Acetyltransferase 2 (Acetoacetyl Coenzyme A Thiolase); Acetyl-CoA Acetyltransferase, Cytosolic; Acetyl-Coenzyme A Acetyltransferase 2; Acetyl-CoA Transferase-Like PR
Species:
Rat
Source:
E. coli
Cat. No.: HY-P701332
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACAT2; Acetoacetyl Coenzyme A Thiolase; Acetyl-CoA Acetyltransferase 2; Acetyl-Coenzyme A Acetyltransferase 2 (Acetoacetyl Coenzyme A Thiolase); Acetyl-CoA Acetyltransferase, Cytosolic; Acetyl-Coenzyme A Acetyltransferase 2; Acetyl-CoA Transferase-Like PR
Species:
Human
Source:
E. coli
Cat. No.: HY-P70047A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding PRotein Li 69p; PeptidylPRolyl Isomerase A; PeptidylPRolyl Isomerase A (Cyclophilin A); CYPA; Peptidyl-PRolyl Cis-Trans Isomerase; Peptidyl-PRolyl Cis-Trans Isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding PR
Species:
Human
Source:
E. coli
Cat. No.: HY-P702967
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: INCENP; Binds And Activates Aurora-B And -C In Vivo And In Vitro; Inner Centromere PRotein; Inner Centromere PRotein Antigens (135kD, 155kD); Inner Centromere PRotein Antigens 135/155kDa; Inner Centromere PRotein INCENP; FLJ31633; Chromosomal Passenger PR
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
