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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
316 Results for "
PR
" in MedChemExpress (MCE) Product Catalog:
Products (316)
316 Results for "PR" in MCE Product Catalog:
Cat. No.: HY-P704771
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
Target:
Research Areas:
BD-9136 is a selective BRD4 PROTAC degrader with a DC50 of 1.2 nM, and exhibits a selectivity of ≥1000-fold over BRD2 and BRD3. BD-9136 preferentially forms a ternary complex with the BD1 domain of BRD4, and downregulates the expression of B7-H4 by disrupting the PR-P300-BRD4 axis. BD-9136 depletes BRD4 protein in tumor tissues, inhibits tumor growth, reduces B7-H4 protein expression, increases CD8+ T cell infiltration, and enhances tumor sensitivity to anti-PD-L1. Degradation of BRD4 by BD-9136 rescues the erythroid differentiation block induced by LSD1 inhibition, and transient administration restores erythroid output while retaining HbF induction. BD-9136 causes no adverse effects in mice at effective doses. BD-9136 can be used in studies related to acute myeloid leukemia, acute lymphoblastic leukemia and breast cancer .
Cat. No.: HY-P7804
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
Cat. No.: HY-P7805
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
Cat. No.: HY-P70153
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
Cat. No.: HY-P70232
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
Cat. No.: HY-P70234
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
Cat. No.: HY-P70891
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERP27; Inactive PRotein Disulfide-Isomerase 27; PRev. C12orf46; ER PRotein 27; PDIA8; FLJ32115; PRotein Disulfide Isomerase Family A, Member 8; Chromosome 12 Open Reading Frame 46; Endoplasmic Reticulum Resident PRotein 27; ERp27; Endoplasmic Reticulum PR
Species:
Human
Source:
HEK293
Cat. No.: HY-P71121
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STMN1; Stathmin 1/OncoPRotein 18; PRev. C1orf215; Metablastin; PRev. LAP18; FLJ32206; OP18; PRosolin; OncoPRotein 18; Chromosome 1 Open Reading Frame 215; Stathmin; Testicular Tissue PRotein Li 189; PR22; Transmembrane PRotein C1orf215; PP19; PhosphoPRote
Species:
Human
Source:
E. coli
Cat. No.: HY-P76644
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SKP1; Transcription Elongation Factor B Polypeptide 1-Like; PRev. SKP1A; Organ Of Corti PRotein 2; TCEB1L; MGC34403; OCP-II; OCP-2; EMC19; SIII; OCP2; RNA Polymerase II Elongation Factor-Like PRotein OCP2; P19A; RNA Polymerase II Elongation Factor-Like PR
Species:
Human
Source:
HEK293
Cat. No.: HY-P71121A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: STMN1; Stathmin 1/OncoPRotein 18; PRev. C1orf215; Metablastin; PRev. LAP18; FLJ32206; OP18; PRosolin; OncoPRotein 18; Chromosome 1 Open Reading Frame 215; Stathmin; Testicular Tissue PRotein Li 189; PR22; Transmembrane PRotein C1orf215; PP19; PhosphoPRote
Species:
Human
Source:
E. coli
Cat. No.: HY-P80737
Synonyms: XRCC5; G22P2; X-ray repair cross-complementing PRotein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair PR
Cat. No.: HY-P700378
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACKR2; CCR9; PRev. CMKBR9; Chemokine Receptor CCR-9; PRev. CCBP2; CC-Chemokine-Binding Receptor JAB61; CCR10; Chemokine (C-C Motif) Receptor 9; D6; Chemokine Binding PRotein 2; Chemokine-Binding PRotein D6; Chemokine (C-C) Receptor 9; Chemokine-Binding PR
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-P703473
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: SKP1; Transcription Elongation Factor B Polypeptide 1-Like; PRev. SKP1A; Organ Of Corti PRotein 2; TCEB1L; MGC34403; OCP-II; OCP-2; EMC19; SIII; OCP2; RNA Polymerase II Elongation Factor-Like PRotein OCP2; P19A; RNA Polymerase II Elongation Factor-Like PR
Species:
Human
Source:
E. coli
Cat. No.: HY-P703474
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SKP1; Transcription Elongation Factor B Polypeptide 1-Like; PRev. SKP1A; Organ Of Corti PRotein 2; TCEB1L; MGC34403; OCP-II; OCP-2; EMC19; SIII; OCP2; RNA Polymerase II Elongation Factor-Like PRotein OCP2; P19A; RNA Polymerase II Elongation Factor-Like PR
Species:
Human
Source:
E. coli
Cat. No.: HY-P704177
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
Cat. No.: HY-P85251
Synonyms: XRCC5; G22P2; X-ray repair cross-complementing PRotein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair PR
Cat. No.: HY-P704747
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
Cat. No.: HY-P704748
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
Cat. No.: HY-P704749
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KRAS; Kras-Enoph1 Fusion PRotein; PRev. KRAS2; PR310 C-K-Ras Oncogene; GTPase KRas; Small Monomeric GTPase; K-Ras4B; C-Kirsten-Ras PRotein; KRAS1; PRoto-Oncogene GTPase; V-Ki-Ras2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog; KRAS-ENOPH Fusion; Kirsten Ra
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
