106 Results for "

DPP-IV

" in MedChemExpress (MCE) Product Catalog:
Products (106)

106 Results for "DPP-IV" in MCE Product Catalog:

Cat. No.: HY-B0422
CAS No.: 105816-04-4
Synonyms: A4166; Senaglinide
Research Areas:  

Metabolic Disease

Nateglinide, a D-phenylalanine derivative, is an orally active and short-acting insulinotropic agent and a DPP IV inhibitor. Nateglinide inhibits ATP-sensitive K + channels in pancreatic β-cells. Nateglinide is used for the treatment of type 2 (non-insulin-dependent) diabetes mellitus .
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Cat. No.: HY-110083
CAS No.: 1017682-66-4
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

PK44 phosphate is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 value of 15.8 nM .
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Cat. No.: HY-U00346
CAS No.: 625110-37-4
Synonyms: DPP-IV-IN-1
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a highly specific serine protease, with an IC50 of 4.6 nM.
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Cat. No.: HY-W031757
CAS No.: 117-78-2
Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities .\n



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Cat. No.: HY-108319
CAS No.: 136259-18-2
Purity:  99.35%
DPP-IV-IN-2 is an inhibitor of both dipeptidyl peptidase IV (DPIV) and DP8/9 with IC50s of 0.1 and 0.95 μM, respectively.
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Cat. No.: HY-111173
CAS No.: 90614-49-6
Purity:  99.70%
Target:  

Dipeptidyl Peptidase

Research Areas:  

Others

Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue .
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Cat. No.: HY-145779
CAS No.: 17663-87-5
Synonyms: H-γ-Glu-Met-OH; γ-Glu-Met
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

H-Glu(Met-OH)-OH (H-γ-Glu-Met-OH; γ-Glu-Met) is a DPP-IV inhibitor with an IC50 of 2.11 mM. H-Glu(Met-OH)-OH binds to DPP-IV’s active site to block substrate binding. H-Glu(Met-OH)-OH can be used for the research of type 2 diabetes .
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Cat. No.: HY-103434
CAS No.: 1017682-65-3
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

PK44 (Compound 67) is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 value of 15.8 nM. PK44 is promising for research of diabetes .
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Cat. No.: HY-W436471
CAS No.: 125791-92-6
Target:  

Inhibitory Antibodies

Research Areas:  

Others

H-Ala-Pro-AFC is a biological active peptide. (This is a fluorescent peptide, Abs/Em=380/500nm. It is a substrate for dipeptidyl peptidase IV (DPP IV) and Xaa-Pro dipeptidase.)
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Cat. No.: HY-P10809
CAS No.: 3103992-61-3
VAMP, a tetrapeptide, is a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 1.00 μM and a Kd of 6.89 μM. VAMP effectively targets the DPP-IV-GLP-1 axis and can be used for the study of type 2 diabetes .
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Cat. No.: HY-14292
CAS No.: 247016-69-9
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

NVP-DPP728 is a potent, reversible and nitrile-dependent dipeptidyl peptidase IV (DPP-IV) inhibitor. NVP-DPP728 can inhibit human DPP-IV amidolytic activity with a Ki of 11 nM. NVP-DPP728 inhibits degradation of glucagon-like peptide-1 (GLP-1) and thereby potentiates insulin release in response to glucose intake. NVP-DPP728 can be used for researching diabetes .
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Cat. No.: HY-P1230
CAS No.: 852155-81-8
Research Areas:  

Metabolic Disease

HAEGT is the first N-terminal 1-5 residues of glucagon like peptide-1 (GLP-1) peptide, and the sequence is His-Ala-Glu-Gly-Thr. HAEGT acts as a competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV (DPP-IV) 1, in which the N-terminal His-Ala is catalyzed cleavage by DPP-IV. HAEGT can be used in the research of diabetes, obesity .
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Cat. No.: HY-B0422S
CAS No.: 1227666-13-8
Synonyms: A4166 d5; Senaglinide d5
Nateglinide-d5 is a deuterium labeled Nateglinide. Nateglinide, a D-phenylalanine derivative, is an orally active and short-acting insulinotropic agent and a DPP IV inhibitor. Nateglinide inhibits ATP-sensitive K+ channels in pancreatic β-cells. Nateglinide is used for the treatment of type 2 (non-insulin-dependent) diabetes mellitus[1][2].
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Cat. No.: HY-14291A
CAS No.: 2133364-01-7
Synonyms: LAF237 dihydrate; NVP-LAF 237 dihydrate
Vildagliptin dihydrate (LAF237 dihydrate) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin dihydrate possesses excellent oral bioavailability and potent antihyperglycemic activity .
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Cat. No.: HY-14291R
CAS No.: 274901-16-5
Synonyms: LAF237 (Standard); NVP-LAF 237 (Standard)
Vildagliptin (Standard) is the analytical standard of Vildagliptin. This product is intended for research and analytical applications. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
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Cat. No.: HY-14291S2
CAS No.: 1044741-01-6
Synonyms: LAF237-13C5,15N; NVP-LAF 237-13C5,15N
Vildagliptin- 13C5, 15N (LAF237- 13C5, 15N; NVP-LAF 237- 13C5, 15N) is a 13C- and 15N-labeled Vildagliptin (HY-14291). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
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Cat. No.: HY-P60234A
CAS No.: 330204-04-1
Research Areas:  

Metabolic Disease

AGFAGDDAPR is a bioactive peptide that is a competitive and orally effective inhibitor of dipeptidyl peptidase-IV (DPP-IV). AGFAGDDAPR can enhance the level of GLP-1 in the body by inhibiting DPP-IV, thereby stimulating insulin secretion, improving β-cell function, and inhibiting abnormal proliferation of α-cells, exerting anti-diabetic effects. AGFAGDDAPR can be used for research on type 2 diabetes .
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Cat. No.: HY-146455
CAS No.: 2402735-14-0
DPP-4-IN-3 (Compound 5a) is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 0.75 nM. DPP-4-IN-3 shows excellent antioxidant and insulinotropic activity .
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Cat. No.: HY-146469
CAS No.: 2010927-65-6
Research Areas:  

Metabolic Disease

DPP-4/GPR119 modulator 2 (Compound 20i) is a dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist with an IC50 of 0.22 μM for DPP-IV and an EC50 of 0.95 μM for GPR119. DPP-4/GPR119 modulator 2 can be used for diabetes research . DPP-4/GPR119 modulator 2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-14291S1
CAS No.: 1133208-42-0
Synonyms: LAF237-d7; NVP-LAF 237-d7
Vildagliptin-d7 is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
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