Diprotin B
Based on 1 Customer Validation
Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue.
For research use only. We do not sell to patients.
- Purity: 99.60%
- CAS No.: 90614-49-6
- Formula: C16H29N3O4
- Molecular Weight:327.42
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 90614-49-6
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Appearance Solid
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Molecular Weight 327.42
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Formula C16H29N3O4
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Color White to off-white
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Sequence Shortening
VPL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (305.42 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
[1]. Rahfeld J, et al. Are diprotin A (Ile-Pro-Ile) and diprotin B (Val-Pro-Leu) inhibitors or substrates of dipeptidyl peptidase IV? Biochim Biophys Acta. 1991 Jan 29;1076(2):314-6. [Content Brief]
[2]. Hatanaka T, et al. Inhibitory effect of collagen-derived tripeptides on dipeptidylpeptidase-IV activity. J Enzyme Inhib Med Chem. 2014 Dec;29(6):823-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.0542 mL | 15.2709 mL | 30.5418 mL | 76.3545 mL |
| 5 mM | 0.6108 mL | 3.0542 mL | 6.1084 mL | 15.2709 mL | |
| 10 mM | 0.3054 mL | 1.5271 mL | 3.0542 mL | 7.6355 mL | |
| 15 mM | 0.2036 mL | 1.0181 mL | 2.0361 mL | 5.0903 mL | |
| 20 mM | 0.1527 mL | 0.7635 mL | 1.5271 mL | 3.8177 mL | |
| 25 mM | 0.1222 mL | 0.6108 mL | 1.2217 mL | 3.0542 mL | |
| 30 mM | 0.1018 mL | 0.5090 mL | 1.0181 mL | 2.5452 mL | |
| 40 mM | 0.0764 mL | 0.3818 mL | 0.7635 mL | 1.9089 mL | |
| 50 mM | 0.0611 mL | 0.3054 mL | 0.6108 mL | 1.5271 mL | |
| 60 mM | 0.0509 mL | 0.2545 mL | 0.5090 mL | 1.2726 mL | |
| 80 mM | 0.0382 mL | 0.1909 mL | 0.3818 mL | 0.9544 mL | |
| 100 mM | 0.0305 mL | 0.1527 mL | 0.3054 mL | 0.7635 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.