1. Metabolic Enzyme/Protease
  2. Dipeptidyl Peptidase
  3. PK44 phosphate

PK44 phosphate is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 value of 15.8 nM.

For research use only. We do not sell to patients.

PK44 phosphate

PK44 phosphate Chemical Structure

CAS No. : 1017682-66-4

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Based on 1 publication(s) in Google Scholar

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Description

PK44 phosphate is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 value of 15.8 nM[1].

IC50 & Target

DPP-4

 

In Vitro

Dipeptidyl peptidase IV (DPP-IV) is a protease that inactivates insulin stimulating hormones such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulin-like polypeptide (GIP). Dipeptidyl peptidase IV can be used as a binding protein and ligand for various extracellular molecules. Dipeptidyl peptidase IV can be used in diabetes research.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

527.34

Formula

C17H19F5N7O5P

CAS No.
SMILES

O=P(O)(O)O.FC(F)(C1=NN=C2N1CCN(C(C[C@H](N)CC(C3=CC=C4F)=NNC3=C4F)=O)C2)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PK44 phosphate
Cat. No.:
HY-110083
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