DPP-4-IN-3
DPP-4-IN-3 (Compound 5a) is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 0.75 nM. DPP-4-IN-3 shows excellent antioxidant and insulinotropic activity.
For research use only. We do not sell to patients.
- CAS No.: 2402735-14-0
- Formula: C19H22N6O2
- Molecular Weight:366.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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DPP-4 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| INS1(832/13) | IC50 |
0.0028 μM
Compound: 5a
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Antidiabetic activity in glucose-treated rat INS1(832/13) cells assessed as increase in insulin release in presence of 3 mM glucose measured after 2 hrs by radioimmunoassay
Antidiabetic activity in glucose-treated rat INS1(832/13) cells assessed as increase in insulin release in presence of 3 mM glucose measured after 2 hrs by radioimmunoassay
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[PMID: 31812034] |
Chemical Information
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CAS No. 2402735-14-0
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Molecular Weight 366.42
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Formula C19H22N6O2
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SMILES
CCOC(N1CCN(CC1)C2=NN3C(C=C2)=NN=C3C4=CC=CC(C)=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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