80 Results for "

FD

" in MedChemExpress (MCE) Product Catalog:
Products (80)

80 Results for "FD" in MCE Product Catalog:

Cat. No.: HY-B2089
CAS No.: 66564-14-5
Cinitapride is a nonselective 5-HT1 and 5-HT4 receptors agonist and a 5-HT2 and D2 antagonist. Cinitapride can be used in functional dyspepsia (FD) and gastroesophageal reflux disease (GERD) research .
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Cat. No.: HY-114461B
CAS No.: 2598242-04-5
Research Areas:  

Cancer

(3S,17S)-FD-895 a FD-895 (HY-114461) analogue, is a spliceosome modulator. (3S,17S)-FD-895 inhibits cancer cell growth and exhibits gene-selective splice modulatory activity. (3S,17S)-FD-895 can be used for the research of colorectal carcinoma .
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Cat. No.: HY-155066
CAS No.: 2641899-38-7
Purity:  99.45%
Target:  

PI3K mTOR Apoptosis

Research Areas:  

Cancer

FD274 is a highly potent PI3K/mTOR dual inhibitor with IC50s of 0.65 nM, 1.57 nM, 0.65 nM, 0.42 nM, and 2.03 nM against PI3Kα/β/γ/δ and mTOR, respectively. FD274 exhibits significant anti-proliferation of AML cell lines (HL-60 and MOLM-16). FD274 arrests HL-60 cell cycle at G1 phase and increases apoptosis. FD274 demonstrates dose-dependent inhibition of tumor growth in the HL-60 xenograft model. FD274 has the potential for acute myeloid leukemia research .
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Cat. No.: HY-148172
CAS No.: 210474-65-0
Research Areas:  

Infection

L-Fd4A is an adenine derivative. L-Fd4A has anti-human immunodeficiency virus (HIV) (EC50=1.5 μM) and anti-hepatitis B virus (HBV) (EC50=1.7 μM) activity. L-Fd4A has low cytotoxicity .
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Cat. No.: HY-P2944
CAS No.: 9029-33-8
Research Areas:  

Metabolic Disease

Ferredoxin-NADP reductase in plants receives electrons from ferredoxin (Fd) at the end of the photosynthetic electron transfer chain and converts NADP + to NADPH .
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Cat. No.: HY-14648S5
Purity:  98.02%
Synonyms: Hexadecadrol-d3-1; Prednisolone F-d3-1
Dexamethasone-d3-1 (Hexadecadrol-d3-1; Prednisolone F-d3-1) is a deuterium labeled Dexamethasone (HY-14648). Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
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Cat. No.: HY-D0307AR
CAS No.: 915-67-3
Synonyms: Acid Red 27 (Standard); Azorubin S (Standard); FD & C Red Dye No. 2 (Standard)
Research Areas:  

Others

Amaranth (Standard) is the analytical standard of Amaranth. This product is intended for research and analytical applications. Amaranth is a dark red to purple azo dye used as a food dye and cosmetics. Amaranth is an anionic dye that can be applied to natural and synthetic fibers, leather, paper, and phenol-formaldehyde resins.
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Cat. No.: HY-114461
CAS No.: 147025-57-8
Research Areas:  

Cancer

FD-895 is a spliceosome modulator derived from a polyketide natural product, targeting the SF3b subunit of the spliceosome. FD-895 possesses core biological activities for regulating RNA splicing (intron retention, alternative splicing) and inducing apoptosis of cancer cells. FD-895 can be used for the research of cancer, such as chronic lymphocytic leukemia (CLL) .
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Cat. No.: HY-155529
CAS No.: 1422456-47-0
Target:  

Pim

Research Areas:  

Cancer

FD1024 is PIM inhibitor (IC50s: 1.96, 38.9, 4.17 nM for PIM1, 2, 3). FD1024 can be used for research of acute myeloid leukemia. FD1024 has strong antiproliferative activity against the tested AML cell lines, with 0.16 μM, 0.12 μM, 1.05 μM, 1.39μM for EOL-1, MV-4-11, KG-1, MOLM-16 cells. FD1024 also has antitumor efficacy in mice .
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Cat. No.: HY-132231
CAS No.: 2050524-24-6
Purity:  98.05%
Target:  

PI3K Apoptosis

Research Areas:  

Cancer

FD223 is a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor. FD223 displays high potency (IC50=1 nM) and good selectivity over other isoforms (IC50s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 exhibits efficient inhibition of the proliferation of acute myeloid leukemia (AML) cell lines by suppressing p-AKT Ser473 thus causing G1 phase arrest during the cell cycle. FD223 has potential for the research of leukemia such as AML .
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Cat. No.: HY-121503
CAS No.: 68207-21-6
Target:  

Others

Research Areas:  

Neurological Disease

FD44 is a phenothiazine small molecule that inhibits the interaction between neuronal calcium sensor 1 (NCS-1) and the guanine exchange factor Ric8a, a key regulator of synapse number and neurotransmitter release probability. In the Drosophila genetic autism model of fragile X syndrome (FXS), FD44 restored normal synapse number and associative learning .
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Cat. No.: HY-128685
CAS No.: 1451741-22-2
Synonyms: Ac12Az9
Target:  

P-glycoprotein BCRP

Research Areas:  

Cancer

FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity .
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Cat. No.: HY-N3921
CAS No.: 126716-36-7
Gancaonin I, an Isoflavone, exhibits moderate inhibition on human carboxylesterase 2 (hCES2A) with IC50 of 1.72 μM. Gancaonin I inhibits hCES2A-mediated fluorescein diacetate (FD) hydrolysis .
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Cat. No.: HY-101748
CAS No.: 62987-05-7
Synonyms: 40497S; FD 1
Research Areas:  

Cancer

Tegadifur is a fluorine-containing and anti-metabolic agent.
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Cat. No.: HY-N3329
CAS No.: 113557-95-2
Magnoloside A (compound 4) is a main phenylethanoid glycoside in Houpo. Magnoloside A can be used in the research of functional dyspepsia (FD) .
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Cat. No.: HY-B2195
CAS No.: 5579-81-7
Target:  

Adrenergic Receptor

Research Areas:  

Metabolic Disease

Aidioxa has the ability to improve delayed gastric emptying in rats. It can partially improve delayed gastric emptying caused by clonidine or restraint stress. The allyltoin part of Aidioxa restores gastric emptying activity by antagonizing α-2 adrenergic receptors. Its aluminum hydroxide part is involved in restoring gastric compliance. Aidioxa can improve both delayed gastric emptying and impaired gastric compliance, both of which play an important role in functional dyspepsia (FD). Aidioxa is a candidate agent for inhibiting FD.
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Cat. No.: HY-13631AS1
Synonyms: DX8951f-d3 mesylate
Exatecan-d3 (DX8951f-d3) mesylate is deuterium-labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 0.975 μg/mL .
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Cat. No.: HY-D0257R
CAS No.: 1934-21-0
Synonyms: Acid Yellow 23 (Standard); FD&C Yellow No. 5 (Standard)
Tartrazine (Standard) is the analytical standard of Tartrazine. This product is intended for research and analytical applications. Tartrazine is an azo acid dye, orange-yellow powder, soluble in water and turns yellow. It is mainly used as a synthetic lemon yellow azo dye for food coloring. It is the most stable colorant.
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Cat. No.: HY-123630R
CAS No.: 25956-17-6
Synonyms: FD&C RED NO. 40 (Standard); CI 16035 (Standard)
Allura Red AC (Standard) is an analytical standard of Allura Red AC. This product is intended for research and analytical applications. Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine (5-HT) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety .
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Cat. No.: HY-B2089R
CAS No.: 66564-14-5
Cinitapride (Standard) is the analytical standard of Cinitapride. This product is intended for research and analytical applications. Cinitapride is a nonselective 5-HT1 and 5-HT4 receptors agonist and a 5-HT2 and D2 antagonist. Cinitapride can be used in functional dyspepsia (FD) and gastroesophageal reflux disease (GERD) research .
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