2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Aldioxa

Aidioxa has the ability to improve delayed gastric emptying in rats. It can partially improve delayed gastric emptying caused by clonidine or restraint stress. The allyltoin part of Aidioxa restores gastric emptying activity by antagonizing α-2 adrenergic receptors. Its aluminum hydroxide part is involved in restoring gastric compliance. Aidioxa can improve both delayed gastric emptying and impaired gastric compliance, both of which play an important role in functional dyspepsia (FD). Aidioxa is a candidate agent for inhibiting FD.

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Aldioxa

Aldioxa Chemical Structure

CAS No. : 5579-81-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 g In-stock
5 g In-stock
10 g In-stock
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Aldioxa Related Antibodies

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α adrenergic receptor β adrenergic receptor

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Description

Aidioxa has the ability to improve delayed gastric emptying in rats. It can partially improve delayed gastric emptying caused by clonidine or restraint stress. The allyltoin part of Aidioxa restores gastric emptying activity by antagonizing α-2 adrenergic receptors. Its aluminum hydroxide part is involved in restoring gastric compliance. Aidioxa can improve both delayed gastric emptying and impaired gastric compliance, both of which play an important role in functional dyspepsia (FD). Aidioxa is a candidate agent for inhibiting FD.

Molecular Weight

218.10

Formula

C4H7AlN4O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1NC(C(NC(O[Al](O)O)=N)N1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 7.14 mg/mL (32.74 mM; ultrasonic and warming and adjust pH to 2 with 1 M HCL and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5851 mL 22.9253 mL 45.8505 mL
5 mM 0.9170 mL 4.5851 mL 9.1701 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.5851 mL 22.9253 mL 45.8505 mL 114.6263 mL
5 mM 0.9170 mL 4.5851 mL 9.1701 mL 22.9253 mL
10 mM 0.4585 mL 2.2925 mL 4.5851 mL 11.4626 mL
15 mM 0.3057 mL 1.5284 mL 3.0567 mL 7.6418 mL
20 mM 0.2293 mL 1.1463 mL 2.2925 mL 5.7313 mL
25 mM 0.1834 mL 0.9170 mL 1.8340 mL 4.5851 mL
30 mM 0.1528 mL 0.7642 mL 1.5284 mL 3.8209 mL
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Aldioxa Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aldioxa5579-81-7Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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