1. Membrane Transporter/Ion Channel
  2. P-glycoprotein
    BCRP
  3. FD 12-9

FD 12-9 (Synonyms: Ac12Az9)

Cat. No.: HY-128685
Handling Instructions

FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity.

For research use only. We do not sell to patients.

FD 12-9 Chemical Structure

FD 12-9 Chemical Structure

CAS No. : 1451741-22-2

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Description

FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity[1].

IC50 & Target

EC50: 0.9 nM (BCRP), 285 nM (P-gp)[1]

Molecular Weight

877.93

Formula

C₅₁H₄₇N₃O₁₁

CAS No.

1451741-22-2

SMILES

O=C(OC)C1=CC=CC(COC2=C(C3=CC=C(OCCOCCOCCN4N=NC(CCCCOC5=CC=C6C(C=C(C7=CC=CC=C7)OC6=C5)=O)=C4)C=C3)OC8=CC=CC=C8C2=O)=C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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FD 12-9
Cat. No.:
HY-128685
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