47 Results for "

GMP+grade

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "GMP+grade" in MCE Product Catalog:

Vorinostat (GMP)
Vorinostat (GMP)
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Cat. No.: HY-10221G
CAS No.: 149647-78-9
Synonyms: SAHA (GMP); Suberoylanilide hydroxamic acid (GMP)
Vorinostat (GMP) is a GMP grade Vorinosta (HY-10221). GMP-grade small molecules can be used as auxiliary agents in cell therapy. Vorinostat is a potent, orally available HDAC1, HDAC2, HDAC3 (Class I), HDAC6 and Inhibitors of HDAC7 (Class II) and Class IV (HDAC11) .
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Hydrocortisone hemisuccinate (GMP)
Hydrocortisone hemisuccinate (GMP)
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Cat. No.: HY-B1402G
CAS No.: 2203-97-6
Synonyms: Hydrocortisone 21-hemisuccinate (GMP)
Hydrocortisone hemisuccinate GMP (Hydrocortisone 21-hemisuccinate GMP) is a GMP-grade version of Hydrocortisone hemisuccinate (HY-B1402). GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate inhibits the bioactivity of IL-6 and IL-3 with IC50 values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers . .
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Bemcentinib (GMP)
Bemcentinib (GMP)
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Cat. No.: HY-15150G
CAS No.: 1037624-75-1
Synonyms: R428 (GMP); BGB324 (GMP)
Bemcentinib (R428) GMP is Bemcentinib (HY-15150) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy.Bemcentinib (R428) is a selective and orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib retards cancer cell migration and invasion. Bemcentinib exhibits >100-fold selectivity for Axl versus Abl and 50- and >100-fold selectivity over TAM family kinases Mer and Tyro3, respectively, in cells. Bemcentinib blocks tumor spread and prolongs survival in models of metastatic breast cancer .
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Fmoc-Val-Cit-PAB (GMP)
Fmoc-Val-Cit-PAB (GMP)
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Cat. No.: HY-19318G
CAS No.: 159858-22-7
Fmoc-Val-Cit-PAB GMP is a GMP grade Fmoc-Val-Cit-PAB (HY-19318). Fmoc-Val-Cit-PAB is a cleavable antibody-conjugated active molecule (ADC) commonly used linker.
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Fmoc-Gly-Gly-Phe-OH (GMP)
Fmoc-Gly-Gly-Phe-OH (GMP)
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Cat. No.: HY-131833G
CAS No.: 160036-44-2
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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Val-Cit-PAB-OSBT (GMP)
Val-Cit-PAB-OSBT (GMP)
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Cat. No.: HY-78736G
CAS No.: 2210262-26-1
Val-Cit-PAB-OSBT GMP is a GMP grade Val-Cit-PAB-OSBT (HY-78736). Val-Cit-PAB-OSBT is a degradable ADC linker, which is composed of the polypeptide Val-Cit-PAB and OSBT groups coupled together .
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TA-316 (GMP)
TA-316 (GMP)
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Cat. No.: HY-112486G
CAS No.: 1429321-13-0
Synonyms: Megakaryocytes/platelets inducing agent (GMP)
TA-316 (GMP) is TA-316 (HY-112486) produced by using GMP guidelines. GMP grade small molecules can be used as auxiliary agents in cell therapy. TA-316 is a c-MPL agonist and a thrombopoietin (TPO) receptor agonist .
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PNU-159682 (GMP)
PNU-159682 (GMP)
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Cat. No.: HY-16700G
CAS No.: 202350-68-3
PNU-159682 GMP is a GMP grade PNU-159682 (HY-16700). PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance.
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DBCO-acid (GMP)
DBCO-acid (GMP)
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Cat. No.: HY-42972G
CAS No.: 1353016-70-2
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)
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Cat. No.: HY-131990G
CAS No.: 1599440-25-1
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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Eprenetapopt (GMP)
Eprenetapopt (GMP)
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Cat. No.: HY-19980G
CAS No.: 5291-32-7
Synonyms: APR-246 (GMP); PRIMA-1Met (GMP)
Eprenetapopt (GMP) (APR-246(GMP)) is Eprenetapopt (HY-19980) in GMP grade. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Eprenetapopt (APR-246) is a first-in-class, small molecule that restores wild-type p53 functions in TP53-mutant cells. Eprenetapopt triggers apoptosis in tumor cells. Eprenetapopt also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance .
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Malic acid (GMP)
Malic acid (GMP)
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Cat. No.: HY-Y1311G
CAS No.: 6915-15-7
Synonyms: Hydroxybutanedioic acid (GMP); E 296 (GMP)
Malic acid (GMP) is Malic acid (HY-Y1311) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle .
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Adjuvant-4 (GMP)
Adjuvant-4 (GMP)
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Cat. No.: HY-153209G
Adjuvant-4 (GMP) is a GMP grade Adjuvant-4. Adjuvant-4 is a vaccine adjuvant that enhances antigen-specific antibody titers and cytotoxic T lymphocyte (CTL) responses . Adjuvant is generally an oil-in-water emulsifier of mineral oil and mannitol monooleate.
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MMAF sodium (GMP)
MMAF sodium (GMP)
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Cat. No.: HY-15579BG
CAS No.: 1799706-65-2
Synonyms: Monomethylauristatin F sodium (GMP)
MMAF sodium GMP is a GMP grade MMAF (sodium) (HY-15579B). MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A .
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Letermovir (GMP)
Letermovir (GMP)
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Cat. No.: HY-15233G
CAS No.: 917389-32-3
Synonyms: AIC246 (GMP); MK-8228 (GMP)
Letermovir (GMP) is the GMP grade of Letermovir (HY-15233). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Letermovir (GMP) is an orally active CMV inhibitor. Letermovir (GMP) targets the CMV terminase complex rather than CMV DNA polymerase and exerts its antiviral activity. Letermovir (GMP) can be used in the study of CMV infection .
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Fmoc-Gly-NH-CH2-acetyloxy (GMP)
Fmoc-Gly-NH-CH2-acetyloxy (GMP)
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Cat. No.: HY-44980G
CAS No.: 1599440-06-8
Fmoc-Gly-NH-CH2-acetyloxy GMP is a GMP grade Fmoc-Gly-NH-CH2-acetyloxy (HY-44980). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).
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Cholicamideβ
Cholicamideβ
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Cat. No.: HY-156087
CAS No.: 3036578-71-6
Target:  

Apoptosis Necroptosis

Research Areas:  

Cancer

Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis .
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Cholicamideβ (GMP)
Cholicamideβ (GMP)
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Cat. No.: HY-156087G
CAS No.: 3036578-71-6
Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis .
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Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)
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Cat. No.: HY-45672G
CAS No.: 1599440-20-6
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .
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