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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
GlyR
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "GlyR" in MCE Product Catalog:
Synonyms: (R)-Alanine (Standard); Ba 2776 (Standard); D-α-Alanine (Standard)
Cat. No.: HY-107782R
CAS No.: 21416-53-5
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Cat. No.: HY-136232
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PSEM 308 hydrochloride is a pharmacologically selective actuator module (PSAM) agonist. PSEM 308 Activates PSAML141F-GlyR chimeric ion channels .
Cat. No.: HY-124550
CAS No.: 55038-27-2
Synonyms: (+)-Sarcophine
Category:
Natural Products Neurological Disease Animals Marine natural products Other marine organisms Disease Research Fields
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Cat. No.: HY-175470
CAS No.: 1874229-27-2
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Stearidonoyl glycine is an N-acyl amino acid. Stearidonoyl glycine has a weak potentiating effect on some glycine receptor subtypes, among which the potentiation on GlyRα2 is statistically significant .
Cat. No.: HY-RS05512
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GLYR1 Human Pre-designed siRNA Set A contains three designed siRNAs for GLYR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22530
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Glyr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Glyr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29050
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Glyr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Glyr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-108940R
CAS No.: 112921-11-6
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GlyRS-IN-1 (Standard) is the analytical standard of GlyRS-IN-1 (HY-108940). This product is intended for research and analytical applications. GlyRS-IN-1 is a GlyRS inhibitor. GlyRS-IN-1 reduces lung metastasis in breast cancer mice. GlyRS-IN-1 can be used in research on breast cancer, non-small cell lung cancer, renal cancer, prostate cancer, ovarian cancer, leukemia, and colon cancer .
Cat. No.: HY-181351
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PSN09 is a blood-brain barrier-permeable agonist of PSAM 4-GlyR and PSAM 4-5-HT3 receptors with high affinity. 18F-labeled PSN09 serves as a radiotracer for PET imaging in non-human primates .
Cat. No.: HY-W741136
CAS No.: 75520-89-7
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(R)-Colchicine is the R-isomer of Colchicine (HY-16569). Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .
Cat. No.: HY-46286
CAS No.: 352560-76-0
Synonyms: N-(4-tert-butyl-1,3-thiazol-2-yl)-3-fluorobenzamide
Research Areas:
TTFB (N-(4-tert-butyl-1,3-thiazol-2-yl)-3-fluorobenzamide) is a selective, non-competitive zinc-activated channel (ZAC) antagonist. TTFB inhibits Zn 2+- and H +-induced ZAC currents with IC50 values of 3 μM and 8.5 μM, respectively, and has an IC50 of 4.7 μM against spontaneous activity. TTFB shows no significant agonistic, antagonistic or modulatory activity towards representative classical Cys-loop receptors including m5-HT3AR, hα3β4 nAChR, hα1β2γ2S GABAAR and hα1 GlyR. TTFB can be used to investigate the physiological and pathological functions of ZAC.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
