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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
Rab7
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "Rab7" in MCE Product Catalog:
Cat. No.: HY-13452R
CAS No.: 314042-01-8
Synonyms: ML282 (Standard)
Target:
Research Areas:
CID-1067700 (Standard) is the analytical standard of CID-1067700 (HY-13452). This product is intended for research and analytical applications. CID-1067700 (ML282) is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM.
Cat. No.: HY-12755R
CAS No.: 71203-35-5
Target:
Research Areas:
ML141 (Standard) is the analytical standard of ML141 (HY-12755). This product is intended for research and analytical applications. ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines .
Cat. No.: HY-RS29509
Target:
Research Areas:
Rab7a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rab7a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Rab7a siRNA-1: 5 nmol (HPLC)
Rab7a siRNA-2: 5 nmol (HPLC)
Rab7a siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
Components
Rab7a siRNA-1: 5 nmol (HPLC)
Rab7a siRNA-2: 5 nmol (HPLC)
Rab7a siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
Cat. No.: HY-P703254
Synonyms: Rab29; Ras-Related Protein Rab-7L1; Prev. Rab7L1; Rab-7-Like Protein 1; Prev. Rab7L; Ras-Related Protein Rab; Rab7, Member RAS Oncogene Family-Like 1; Rab29, Member RAS Oncogene Family; Ras-Related Protein Rab-29
Species:
Human
Source:
E. coli
Cat. No.: HY-183772
Target:
Research Areas:
TBC1D2-IN-1 is a potent orally active and selective TBC1D2 inhibitor with a Kd of 1.1 μM. TBC1D2-IN-1 selectively inhibits TBC1D2-mediated GTP hydrolysis on RAB7A-GTP, promotes RAB7A accumulation on lysosomal membranes, and induces apoptosis and autophagy. TBC1D2-IN-1 exerts selective antiproliferative activity cancer cells. TBC1D2-IN-1 can be used for the research of cervical carcinoma .
Cat. No.: HY-187218
TBC1D2-IN-2 is an orally potent TBC1D2 inhibitor that binds to the TBC1D2 PH domain with a KD of 0.4 μM. TBC1D2-IN-2 induces autophagic cell death by reducing TBC1D2 protein levels, promoting RAB7A aggregation and enhancing autophagy. TBC1D2-IN-2 can be used in the research of hepatocellular carcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
