Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
69 Results for "
SMC
" in MedChemExpress (MCE) Product Catalog:
Products (69)
69 Results for "SMC" in MCE Product Catalog:
Cat. No.: HY-RS13419
Target:
Research Areas:
SMC3 Human Pre-designed siRNA Set A contains three designed siRNAs for SMC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13420
Target:
Research Areas:
SMC4 Human Pre-designed siRNA Set A contains three designed siRNAs for SMC4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13421
Target:
Research Areas:
SMC5 Human Pre-designed siRNA Set A contains three designed siRNAs for SMC5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13422
Target:
Research Areas:
SMC6 Human Pre-designed siRNA Set A contains three designed siRNAs for SMC6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18370
Target:
Research Areas:
Smc3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Smc3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13416
Target:
Research Areas:
SMC1A Human Pre-designed siRNA Set A contains three designed siRNAs for SMC1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22809
Target:
Research Areas:
Smc1a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Smc1a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13417
Target:
Research Areas:
SMC1B Human Pre-designed siRNA Set A contains three designed siRNAs for SMC1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04080
Target:
Research Areas:
DYM Human Pre-designed siRNA Set A contains three designed siRNAs for DYM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-A0013AR
CAS No.: 157212-55-0
Research Areas:
Bosentan (hydrate) (Standard) is the analytical standard of Bosentan (hydrate). This product is intended for research and analytical applications. Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
Cat. No.: HY-135374
CAS No.: 131275-93-9
Target:
Research Areas:
(3R,5S)-Atorvastatin sodium is an impurity of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively .
Cat. No.: HY-W707564
Cat. No.: HY-135390
CAS No.: 253688-62-9
Synonyms: Ro 64-1056
Target:
Research Areas:
Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver . Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Bosentan can be used in treatment of pulmonary arterial hypertension .
Cat. No.: HY-RS20820
Target:
Research Areas:
Smc4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Smc4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24849
Target:
Research Areas:
Smc3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Smc3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27334
Target:
Research Areas:
Smc4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Smc4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29324
Target:
Research Areas:
Smc1a Rat Pre-designed siRNA Set A contains three designed siRNAs for Smc1a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-189364
CAS No.: 88262-44-6
Synonyms: SMC247-9
Target:
Research Areas:
(DL)-3,5-Dimethyltyrosine (SMC247-9) is a selective APOBEC3B inhibitor optimized from SMC247, with an IC50 of 50 pM. (DL)-3,5-Dimethyltyrosine binds to the APOBEC3B protein, reduces intracellular APOBEC3B protein abundance partially through a lysosome-dependent pathway, enhances IL-15 expression in tumor cells, and relieves the suppression of CD8 + T cells by tumor cells in an IL-15-dependent manner. (DL)-3,5-Dimethyltyrosine attenuates tumor- and macrophage-derived chemokine-mediated macrophage chemotaxis and inhibits pathological myeloid inflammatory signaling. (DL)-3,5-Dimethyltyrosine inhibits tumor growth in the immune checkpoint blockade-responsive MC38 syngeneic mouse model and produces synergistic effects with anti-PD-L1 in the immune checkpoint blockade-resistant TC-1 tumor model; it also ameliorates anti-PD-1-exacerbated DSS-induced colitis-like intestinal inflammatory injury. (DL)-3,5-Dimethyltyrosine can be used in research related to tumor immunotherapy .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
