787 Results for "

Screening

" in MedChemExpress (MCE) Product Catalog:
Products (787)

787 Results for "Screening" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-W019823
CAS No.: 76204-02-9
4-MUNANA is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU). By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses .
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2
2 Cited Publications
Cat. No.: HY-N8599
CAS No.: 531-58-8
Cichoriin is an orally active coumarin glycoside with broad biological activities. Cichoriin exhibits inhibitory activities against α-amylase, α-glucosidase, pancreatic lipase and DPP-IV, with IC50 values of 5.76, 2.94, 16.83 and 9.16 μg/mL, respectively. Cichoriin significantly improves metabolic dysfunction-associated steatohepatitis (MASH) in mice by activating the AMPK signaling pathway. Cichoriin upregulates PPAR-γ in adipose tissue and alleviates obesity and associated cardiorenal injury in rats. Cichoriin blocks monosodium urate crystal-induced activation of the NLRP3 inflammasome and cell pyroptosis by inhibiting P2Y14R (IC50 = 8.47 nM). In silico virtual screening reveals that Cichoriin has a strong binding affinity for SARS-CoV-2 .
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2 Cited Publications
Cat. No.: HY-B1186
CAS No.: 502-55-6
Research Areas:  

Others

Dixanthogen is a dimer of xanthate, which forms via the oxidation of xanthate. Dixanthogen can decompose peroxides, which are key radical initiators for the oxidative degradation of polypropylene. Dixanthogen serves as a stabilizer for polypropylene, a pediculicide, and is also used in studies related to metal recovery .
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1
1 Cited Publications
Cat. No.: HY-P4917A
Synonyms: SST 14 TFA
Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Somatostatin-14 (reduced) (SST 14) TFA is a polypeptide that can be found by peptide screening .
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1
1 Cited Publications
Cat. No.: HY-P4917
CAS No.: 40958-31-4
Synonyms: SST 14
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Somatostatin-14 (reduced) (SST 14) is a polypeptide that can be found by peptide screening .
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1 Cited Publications
Cat. No.: HY-19639
CAS No.: 858102-78-0
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

E-982 is a steroid used for the on-line screening of the DNA unwinding element binding protein (DUE-B) immobilized protein column .
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1 Cited Publications
Cat. No.: HY-W020658
CAS No.: 97281-52-2
L-α-Phosphatidylinositol is a type of phospholipid. L-α-Phosphatidylinositol can serve as an antigen in ELISA assays for screening antiphospholipid antibodies. L-α-Phosphatidylinositol can be used in studies related to HIV-1 infection .
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1
1 Cited Publications
Cat. No.: HY-117002
CAS No.: 1030769-75-5
Purity:  98.92%
Target:  

Wnt

Research Areas:  

Cancer

SRI 37892 is a small molecule compound inhibitor of Frizzled protein 7 (Fzd7) with inhibitory activity against cancer cell proliferation (IC50=2μM). SRI 37892 significantly blocks Wnt/Fzd7 signaling. SRI 3789 can be used in the research of developing cancer therapeutic agents .
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1 Cited Publications
Cat. No.: HY-148137
CAS No.: 851212-80-1
Purity:  99.84%
Target:  

Cannabinoid Receptor

Research Areas:  

Neurological Disease

CB1 agonist 1 (compound 22) is an agonist of CB1. CB1 agonist 1 shows affinity to CB1 receptor with an pIC50 value of 5.7. CB1 agonist 1 can be used for the research of brain disorders .
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1 Cited Publications
Cat. No.: HY-W783415
CAS No.: 1424357-72-1
Target:  

FAK

Research Areas:  

Cancer

STARD3-IN-1 (Compound VS1) is a STARD3 inhibitor with an IC₅₀ of 35 μM. STARD3 is a protein that is overexpressed in various cancers and is involved in cholesterol transport. STARD3-IN-1 exhibits anti-proliferative activity in breast cancer and colon cancer cells, significantly weakening the clonogenic ability of cancer cells. STARD3-IN-1 increases the protein levels of FAK and pTyr397-FAK. STARD3-IN-1 can be used for research on breast cancer and colon cancer .
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1 Cited Publications
Cat. No.: HY-113100
CAS No.: 18233-70-0
Purity:  ≥99.0%
N-Acetylputrescine hydrochloride is a polyamine metabolite that regulates cell proliferation and signal transduction mainly by participating in polyamine acetylation modification. N-Acetylputrescine hydrochloride may reduce the positive charge of polyamines, affect protein-nucleic acid interactions, and promote cell growth. The concentration changes of N-Acetylputrescine hydrochloride can help disease diagnosis (such as early screening and efficacy evaluation of lung cancer) and microbial cell wall structure research. N-Acetylputrescine hydrochloride can be used as a potential biomarker for the progression of squamous cell carcinoma of the lung (SCCL) and Parkinson's disease (PD) .
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1 Cited Publications
Cat. No.: HY-W342604
CAS No.: 5699-41-2
Synonyms: NAP
N-Acetylputrescine is a polyamine metabolite that regulates cell proliferation and signal transduction mainly by participating in polyamine acetylation modification. N-Acetylputrescine may reduce the positive charge of polyamines, affect protein-nucleic acid interactions, and promote cell growth. The concentration changes of N-Acetylputrescine can help disease diagnosis (such as early screening and efficacy evaluation of lung cancer) and microbial cell wall structure research. N-Acetylputrescine can be used as a potential biomarker for the progression of squamous cell carcinoma of the lung (SCCL) and Parkinson's disease (PD) .
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1 Cited Publications
Cat. No.: HY-50861
CAS No.: 892489-52-0
Target:  

Acyltransferase

Research Areas:  

Metabolic Disease

AZD3988 is an orally active diacylglycerol acyl transferase-1 (DGAT-1) inhibitor. AZD3988 has excellent DGAT-1 (human) potency with an IC50 value of 0. 6 nM. AZD3988 can be used for the research of metabolic diseases such as diabetes, obesity .
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1 Cited Publications
Cat. No.: HY-N6841
CAS No.: 86831-53-0
Rhodiolin, a flavonoid, is an orally active glucose 6-phosphate isomerase (GPI) inhibitor. Rhodiolin inhibits papillary thyroid cancer (PTC) by targeting glycolysis enzyme glucose 6-phosphate isomerase GPI and suppressing PI3K/AKT/mTOR phosphorylation and induce apoptosis. Rhodiolin as a NS2B-NS3 protease inhibitor can disrupt dengue viral replication. Rhodiolin is also a potential candidate for developing anticancer strategies inhibiting CK1ε kinase. Rhodiolin can be used for the study of anti-tumor and anti-viral .
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Cat. No.: HY-P4424
CAS No.: 60461-10-1
Synonyms: Met-Arg
Target:  

Inhibitory Antibodies

Research Areas:  

Others

H-Met-Arg-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Cat. No.: HY-P4509
CAS No.: 16875-28-8
Synonyms: Ser-Phe
Target:  

Inhibitory Antibodies

Research Areas:  

Others

H-Ser-Phe-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Cat. No.: HY-P4825
CAS No.: 78232-94-7
Target:  

Inhibitory Antibodies

Research Areas:  

Others

pTH (1-38) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Cat. No.: HY-P4261
CAS No.: 2418-67-9
Target:  

Inhibitory Antibodies

Research Areas:  

Others

L-Arginylglycine is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Cat. No.: HY-P4723
CAS No.: 1188922-20-4
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Intermedin (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Cat. No.: HY-P4644
CAS No.: 13123-35-8
Synonyms: NSC 286600
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Tryptophylleucine (NSC 286600) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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