2. Protein Tyrosine Kinase/RTK
  3. FAK
  4. STARD3-IN-1

STARD3-IN-1 (Compound VS1) is a STARD3 inhibitor with an IC₅₀ of 35 μM. STARD3 is a protein that is overexpressed in various cancers and is involved in cholesterol transport. STARD3-IN-1 exhibits anti-proliferative activity in breast cancer and colon cancer cells, significantly weakening the clonogenic ability of cancer cells. STARD3-IN-1 increases the protein levels of FAK and pTyr397-FAK. STARD3-IN-1 can be used for research on breast cancer and colon cancer.

For research use only. We do not sell to patients.

STARD3-IN-1

STARD3-IN-1 Chemical Structure

CAS No. : 1424357-72-1

Size Price Stock Quantity
5 mg Get quote 4 - 6 weeks 3 - 5 weeks 5 - 7 weeks 3 - 5 weeks
10 mg Get quote 4 - 6 weeks 3 - 5 weeks 5 - 7 weeks 3 - 5 weeks
25 mg Get quote 4 - 6 weeks 3 - 5 weeks 5 - 7 weeks 3 - 5 weeks
50 mg Get quote 4 - 6 weeks 3 - 5 weeks 5 - 7 weeks 3 - 5 weeks
100 mg Get quote 4 - 6 weeks 3 - 5 weeks 5 - 7 weeks 3 - 5 weeks
200 mg   Get quote  
500 mg   Get quote  
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Based on 1 publication(s) in Google Scholar

STARD3-IN-1 Related Antibodies

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Description

STARD3-IN-1 (Compound VS1) is a STARD3 inhibitor with an IC₅₀ of 35 μM. STARD3 is a protein that is overexpressed in various cancers and is involved in cholesterol transport. STARD3-IN-1 exhibits anti-proliferative activity in breast cancer and colon cancer cells, significantly weakening the clonogenic ability of cancer cells. STARD3-IN-1 increases the protein levels of FAK and pTyr397-FAK. STARD3-IN-1 can be used for research on breast cancer and colon cancer[1].

Molecular Weight

404.42

Formula

C22H20N4O4
CAS No.
Appearance

Powder

Color

Orange to red

SMILES

O=C(NC(/C=C/C1=CC([N+]([O-])=O)=C(O)C=C1)=N2)C3=C2CN(CC4=CC=CC=C4)CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (12.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4727 mL 12.3634 mL 24.7268 mL
5 mM 0.4945 mL 2.4727 mL 4.9454 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4727 mL 12.3634 mL 24.7268 mL 61.8169 mL
5 mM 0.4945 mL 2.4727 mL 4.9454 mL 12.3634 mL
10 mM 0.2473 mL 1.2363 mL 2.4727 mL 6.1817 mL
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STARD3-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STARD3-IN-11424357-72-1FAKPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseSTARD3 inhibitorvirtual screeningbreast and colon cancerscholesterol transportanticancer agentInhibitorinhibitorinhibit

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