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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
excitable cells
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "excitable cells" in MCE Product Catalog:
Cat. No.: HY-DY1101
CAS No.: 108964-32-5
Synonyms: Fura-2 Acetoxymethyl ester (solution)
Solvent and concentration: DMSO: 1 mM
Cat. No.: HY-123320
CAS No.: 69409-94-5
Target:
Research Areas:
Fluvalinate is an orally active acaricide classified as a sodium channel inhibitor. Fluvalinate delays sodium channel closure, prolongs cell membrane depolarization, inhibits the excitability of honeybee brain neurons, and exerts a central nervous system inhibitory effect. Fluvalinate negatively affects the learning ability, memory ability, sucrose responsiveness, and survival of honeybees. Fluvalinate potentiates pentobarbital-induced hypnosis, reduces spontaneous activity in mice, and decreases the total white blood cell count and absolute lymphocyte count in mice. Fluvalinate induces acute toxic symptoms in rats, acts as a cholinergic stimulant, and induces the production of hepatic enzymes in rats. Fluvalinate causes the death of Varroa jacobsoni sensitive to τ-Fluvalinate (HY-B2021). Fluvalinate can be used in studies related to mite pest control .
Cat. No.: HY-A0236AR
CAS No.: 33237-74-0
Research Areas:
Aprindine hydrochloride (Standard) is the analytical reference standard of Aprindine hydrochloride (HY-A0236A). This product is used for research and analytical applications. Aprindine hydrochloride is an Ib-class anti-arrhythmic agent. Aprindine hydrochloride mainly exerts its effect by blocking sodium channels (INa), thereby reducing the excitability and conduction velocity of cardiac muscle cells. Aprindine hydrochloride significantly inhibits delayed potassium currents, which helps to prolong the atrial effective refractory period (AERP) and inhibit the occurrence of atrial fibrillation. Aprindine hydrochloride can also regulate intracellular calcium ion concentration by inhibiting Na +/Ca 2+ exchange current (INCX), thereby further stabilizing cardiac electrical activity. Aprindine hydrochloride can be used for the study of atrial fibrillation (AF) and ventricular arrhythmias.
Cat. No.: HY-D3146
CAS No.: 1418017-91-0
Target:
Research Areas:
Di-4-AN (F) EPPTEA is a voltage-sensitive dye used for membrane potential imaging and optical recording of electrical activity in excitable cells and tissues. Its detection mechanism is based on electrochromism (also known as the molecular Stark effect). The single-photon excitation/emission wavelengths measured in ethanol solution are Ex/Em = 444/610 nm, and it can be excited via 1064 nm two-photon excitation in optical recording applications. Di-4-AN (F) EPPTEA can be used to record backpropagating action potentials in individual dendritic spines of brain cortical slices, map subcellular action potential characteristics of single cardiomyocytes, and perform real-time recording of multicellular action potentials in cerebellar slices .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
