229 Results for "

hydroxypropyl+cyclodextrin+uses

" in MedChemExpress (MCE) Product Catalog:
Products (229)

229 Results for "hydroxypropyl+cyclodextrin+uses" in MCE Product Catalog:

1
Cyclo(RADfK)
Cyclo(RADfK)
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1 Cited Publications
製品番号: HY-P0031
CAS 番号: 756500-23-9
Target:  

Integrin

研究分野:  

Others

Cyclo(RADfK) can be used as a control for Cyclo(-RGDfK) (HY-P0023) .
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Cyclosomatostatin
Cyclosomatostatin
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1 Cited Publications
製品番号: HY-P1201
CAS 番号: 84211-54-1
Target:  

Somatostatin Receptor Opioid Receptor

研究分野:  

Inflammation/Immunology Cancer

Cyclosomatostatin is a non-selective somatostatin receptor antagonist that blocks SSTR1-5-mediated signaling. Cyclosomatostatin decreases the ALDH + stem cell population and sphere formation without affecting cell viability, and reduces cell proliferation. Cyclosomatostatin activates opioid receptors. Cyclosomatostatin can be used for research on arthritis and colorectal cancer .
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Didemnin B
Didemnin B
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1 Cited Publications
製品番号: HY-105055
CAS 番号: 77327-05-0
純度:  99.95%
Category:  

天然物 Animals Marine natural products Other marine organisms Disease Research Fields Cancer

Target:  

Others

Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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Astressin 2B
Astressin 2B
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1 Cited Publications
製品番号: HY-P1108
CAS 番号: 681260-70-8
Target:  

CRFR

研究分野:  

Neurological Disease Inflammation/Immunology

Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
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Astressin 2B TFA
Astressin 2B TFA
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1 Cited Publications
製品番号: HY-P1108A
Target:  

CRFR

研究分野:  

Neurological Disease Inflammation/Immunology

Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
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Cyclo(his-pro)
Cyclo(his-pro)
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製品番号: HY-101402
CAS 番号: 53109-32-3
別名: Cyclohistidyl-proline; Histidylproline diketopiperazine
Category:  

天然物 Endogenous metabolite

Target:  

NF-κB Endogenous Metabolite

Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .
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Cyclo(L-Pro-L-Val)
Cyclo(L-Pro-L-Val)
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製品番号: HY-P1938
CAS 番号: 2854-40-2
Category:  

天然物 Microorganisms

Target:  

Bacterial

Cyclo(L-Pro-L-Val) is an antimicrobial and anti-inflammatory agent. Cyclo(L-Pro-L-Val) has toxic activity against plant pathogens such as R. fascians LMG 3605, and its potency may be comparable to that of Chloramphenicol (HY-B0239). Cyclo(L-Pro-L-Val) can inhibit the phosphorylation of IKKα, IKKβ, NF-κB, etc., and the activation of iNOS and COX-2, thereby exerting anti-inflammatory activity. Cyclo(L-Pro-L-Val) can be used in the research of biopesticides in the agricultural field, as well as in the research of inflammation-related diseases .
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Cyclo(Arg-Pro)
Cyclo(Arg-Pro)
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製品番号: HY-P10304
CAS 番号: 74838-83-8
別名: Cyclo(Pro-Arg)
Target:  

Fungal

研究分野:  

Others

Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .
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CPI1
CPI1
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製品番号: HY-P10856
CAS 番号: 3085809-95-3
Target:  

P-glycoprotein

研究分野:  

Cancer

CPI1 is a multidrug resistance protein 1 (MRP1) inhibitor with a Ki value of 100 nM. CPI1 binds to the same substrate-binding site as leukotriene C4, stabilizes MRP1 in an apo-like inward-facing conformation, blocks the conformational changes required for ATP hydrolysis and substrate transport, and inhibits the ATPase activity of human and bovine MRP1. CPI1 serves as a tool for investigating the substrate transport mechanism of MRP1. CPI1 is applicable to research related to cancer multidrug resistance .
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NP213 TFA
NP213 TFA
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製品番号: HY-126810A
純度:  99.80%
Target:  

Fungal

研究分野:  

Infection

NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .
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Cyclo(Gly-L-Pro)
Cyclo(Gly-L-Pro)
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製品番号: HY-P1936
CAS 番号: 3705-27-9
Category:  

Alkaloids Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Plants Araliaceae

Target:  

Others

Cyclo(Gly-L-Pro) is a Alkaloids product that can be isolated from the roots of Panax notoginseng (Burk.)F.H.Chen .
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Cyclo(his-pro) TFA
Cyclo(his-pro) TFA
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製品番号: HY-101402A
CAS 番号: 936749-56-3
純度:  99.06%
別名: Cyclohistidyl-proline TFA; Histidylproline diketopiperazine TFA
Category:  

天然物 Endogenous metabolite

Target:  

NF-κB Endogenous Metabolite

Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) TFA could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) TFA can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .
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Cyclo(Ala-Gly)
Cyclo(Ala-Gly)
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製品番号: HY-75564
CAS 番号: 4526-77-6
Category:  

天然物 Microorganisms Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite

Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC50 values range from 9.5 to 18.1 μM .
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Cyclo(CKLIIF) TFA
Cyclo(CKLIIF) TFA
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製品番号: HY-P10221A
Target:  

HIF/HIF Prolyl-Hydroxylase

研究分野:  

Cancer

Cyclo(CKLIIF) TFA is an inhibitor of HIF-1α and HIF-2α. The KD values of Cyclo(CKLIIF) TFA for the PAS-B domains of HIF1-α and HIF2-α are 2.6 μM and 2.2 μM, respectively. Cyclo(CKLIIF) TFA disrupts the protein-protein interaction between HIF-1α and HIF-1β. Cyclo(CKLIIF) TFA can be used in cancer research .
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cyclo(CLLFVY)
cyclo(CLLFVY)
0 Images
製品番号: HY-P10426
CAS 番号: 1446322-73-1
Target:  

HIF/HIF Prolyl-Hydroxylase VEGFR

研究分野:  

Cancer

cyclo(CLLFVY) is an inhibitor for hypoxia inducible factor-1 (HIF-1), with IC50 of 19 μM (in U2OS) and 16 μM (in MCF-7). cyclo(CLLFVY) binds to the PAS-B domain of HIF-1α, inhibits HIF-1 dimerization and transcriptional activity. cyclo(CLLFVY) downregulates the expression of hypoxia response genes, such as VEGF and CAIX, exhibits antitumor against the HIF-1 associated cancers .
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Cyclo(-Leu-Phe)
Cyclo(-Leu-Phe)
0 Images
製品番号: HY-P4617
CAS 番号: 7280-77-5
Target:  

阻害性抗体

研究分野:  

Others

Cyclo(-Leu-Phe) is a cyclic peptide composed of leucine and phenylalanine, forming a ring structure through peptide bonds .
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OK2
OK2
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製品番号: HY-P5314
CAS 番号: 2983020-14-8
Target:  

EGFR STAT

研究分野:  

Others

OK2, a specific inhibitor of the CCN2/EGFR interaction, efficiently blocks CCN2/EGFR interaction through binding to the CT domain of CCN2. OK2 can be used for kidney fibrosis and chronic kidney disease research .
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Cyclo(Tyr-Leu)
Cyclo(Tyr-Leu)
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製品番号: HY-131115
CAS 番号: 82863-65-8
純度:  98.92%
Category:  

天然物 Portulacaceae Other Diseases Plants Portulaca oleracea Linn. Disease Research Fields

Target:  

Others

Cyclo(Tyr-Leu) is a cyclic dipeptide .
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NP213
NP213
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製品番号: HY-126810
CAS 番号: 942577-31-3
Target:  

Fungal

研究分野:  

Infection

NP213 is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 is effective and well-tolerated in resolving nail fungal infections .
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Cyclo(RGDfK(Mal))
Cyclo(RGDfK(Mal))
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製品番号: HY-P4047
CAS 番号: 1228992-90-2
Target:  

Drug Derivative

研究分野:  

Others

Cyclo(RGDfK(Mal)) is a pentapeptide. Cyclo(RGDfK(Mal)) improves the attachment and infiltration of human pluripotent stem cells. Cyclo(RGDfK(Mal)) can be used for 3D stem cell culture and expansion .
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