2854-40-2
Chemical Structure
Cyclo(L-Pro-L-Val)
- CAS No.: 2854-40-2
- Formula:C10H16N2O2
- Molecular Weight:196.25
InChIKey: XLUAWXQORJEMBD-YUMQZZPRSA-N
SMILES: O=C(N[C@H]1C(C)C)[C@@](CCC2)([H])N2C1=O
Biological Activity: Cyclo(L-Pro-L-Val) is an antimicrobial and anti-inflammatory agent. Cyclo(L-Pro-L-Val) has toxic activity against plant pathogens such as R. fascians LMG 3605, and its potency may be comparable to that of Chloramphenicol (HY-B0239). Cyclo(L-Pro-L-Val) can inhibit the phosphorylation of IKKα, IKKβ, NF-κB, etc., and the activation of iNOS and COX-2, thereby exerting anti-inflammatory activity. Cyclo(L-Pro-L-Val) can be used in the research of biopesticides in the agricultural field, as well as in the research of inflammation-related diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cyclo(L-Pro-L-Val) | 98.52% | Cyclo(L-Pro-L-Val) is an antimicrobial and anti-inflammatory agent. Cyclo(L-Pro-L-Val) has toxic activity against plant pathogens such as R. fascians LMG 3605, and its potency may be comparable to that of Chloramphenicol (HY-B0239). Cyclo(L-Pro-L-Val) can inhibit the phosphorylation of IKKα, IKKβ, NF-κB, etc., and the activation of iNOS and COX-2, thereby exerting anti-inflammatory activity. Cyclo(L-Pro-L-Val) can be used in the research of biopesticides in the agricultural field, as well as in the research of inflammation-related diseases. | ||||||||||||||||||||
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Cyclo(L-Pro-L-Val) (Standard) | ≥98% | Cyclo(L-Pro-L-Val) (Standard) is the analytical standard of Cyclo(L-Pro-L-Val). This product is intended for research and analytical applications. Cyclo(L-Pro-L-Val) is a 2,5-diketopiperazine, with toxic activity against phytopathogenic microorganisms (such as R. fascians LMG 3605). Cyclo(L-Pro-L-Val) shows toxicity similar to Chloramphenicol (HY-B0239) with comparable concentration. Cyclo(L-Pro-L-Val) can also inhibit gram-positive phytopathogenic bacterium. Cyclo(L-Pro-L-Val) has potential development as biopesticide. | ||||||||||||||||||||
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References
- [1]. Cimmino A, et al. Isolation of 2,5-diketopiperazines from Lysobacter capsici AZ78 with activity against Rhodococcus fascians. Nat Prod Res. 2021 Dec;35(23):4969-4977. [Content Brief]
- [2]. Lee D, et al. Bioactive Phytochemicals from Mulberry: Potential Anti-Inflammatory Effects in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. Int J Mol Sci. 2021 Jul 29;22(15):8120. [Content Brief]
