50 Results for "

cell encapsulation

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "cell encapsulation" in MCE Product Catalog:

Cat. No.: HY-129228
CAS No.: 77448-64-7
Lychnopholide is a sesquiterpene lactone derived from the Asteraceae, Lychnopholide exhibits anti-trypanosomal activity against Trypanosoma cruzi. lychnopholide encapsulated in nanocapsules reduces its toxicity to mammalian cells. Lychnopholide ameliorates Chagas disease in mouse models .
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Cat. No.: HY-169480
CAS No.: 3003022-09-8
Target:  

Liposome

Research Areas:  

Infection Cancer

Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3 +CD8 + central and CD3 +CD8 + effector memory T cells and decrease the percentage of CD3 + T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model .
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Cat. No.: HY-172335
Target:  

Liposome

Research Areas:  

Others

C9-200 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs). C9-200-based LNPs encapsulating mRNA encoding erythropoietin (EPO) can induced EPO production and stimulate red blood cell production in mice .
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Cat. No.: HY-117909
CAS No.: 1456608-94-8
Synonyms: RXDX-107
Target:  

Apoptosis

Research Areas:  

Cancer

CEP-40125 (RXDX-107) is a modified form of Bendamustine (HY-13567), a DNA cross-linking agent that may cause DNA damage and cell apoptosis. CEP-40125 (RXDX-107) is formed by encapsulating the alkyl ester form of Bendamustine in human serum albumin .
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Cat. No.: HY-168943A
PLGA nanoparticles, 200nm, are biodegradable tumor-targeting nanocarriers that can serve as drug delivery enhancers and multidrug resistance inhibitors. PLGA nanoparticles, 200nm, passively enriched through the EPR effect and actively targeted via ligand-mediated endocytosis, can encapsulate various antitumor active molecules. PLGA nanoparticles, 200nm can specifically recognize multiple types of tumor cells and improve cellular uptake, cytotoxicity and antiproliferative effects after modification with ligands such as transferrin, folic acid, and RGD. PLGA nanoparticles, 200nm can encapsulate various therapeutic drugs and can be surface modified to achieve targeting, imaging, and prolonged circulation time, making them suitable for cancer-related research .
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Cat. No.: HY-168943B
PLGA nanoparticles, 500nm, are biodegradable tumor-targeting nanocarriers that can serve as drug delivery enhancers and multidrug resistance inhibitors. PLGA nanoparticles, 500nm, passively enriched through the EPR effect and actively targeted via ligand-mediated endocytosis, can encapsulate various antitumor active molecules. PLGA nanoparticles, 500nm can specifically recognize multiple types of tumor cells and improve cellular uptake, cytotoxicity and antiproliferative effects after modification with ligands such as transferrin, folic acid, and RGD. PLGA nanoparticles, 500nm can encapsulate various therapeutic drugs and can be surface modified to achieve targeting, imaging, and prolonged circulation time, making them suitable for cancer-related research .
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Cat. No.: HY-168943C
PLGA nanoparticles, 1μm, are biodegradable tumor-targeting nanocarriers that can serve as drug delivery enhancers and multidrug resistance inhibitors. PLGA nanoparticles, 1μm, passively enriched through the EPR effect and actively targeted via ligand-mediated endocytosis, can encapsulate various antitumor active molecules. PLGA nanoparticles, 1μm can specifically recognize multiple types of tumor cells and improve cellular uptake, cytotoxicity and antiproliferative effects after modification with ligands such as transferrin, folic acid, and RGD. PLGA nanoparticles, 1μm can encapsulate various therapeutic drugs and can be surface modified to achieve targeting, imaging, and prolonged circulation time, making them suitable for cancer-related research .
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Cat. No.: HY-19873
CAS No.: 925438-34-2
Target:  

Photosensitizer

Research Areas:  

Cancer

SL-052 is a hypocrellin-based photosensitizer that has recently shown promising results in clinical and preclinical testing for cancer photodynamic therapy (PDT). SL-052 is encapsulated in biodegradable polylactic-co-glycolic acid (PLGA) polymer nanoparticles optimized using single emulsion solvent evaporation technology. The SL-052-PLGA nanoparticles were more effective in PDT treatment of subcutaneous SCCVII squamous cell carcinoma compared to polyvinylpyrrolidone (PVP)-based and standard liposomal SL-052 formulations. A longer time interval between drug injection and tumor illumination can improve tumor cure rates, and SL-052-PLGA nanoparticles showed the best therapeutic effect among all SL-052 formulations.
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Cat. No.: HY-188103
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL4 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL4 mRNA. Human IL4 mRNA encapsulates human interleukin 4 (IL4) protein, a pleiotropic cytokine produced by activated T cells that regulates various T and B cell responses, including cell proliferation, survival, and gene expression.
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Cat. No.: HY-188107
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CD70 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating human CD70 mRNA. Human CD70 mRNA encapsulates the human CD70 molecule (CD70) protein. CD70 induces co-stimulatory T cell proliferation, enhances the generation of cytolytic T cells, and promotes T cell activation.
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Cat. No.: HY-188104
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL2 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL2 mRNA. Human IL2 mRNA encapsulates human interleukin 2 (IL2) protein, which belongs to the interleukin 2 (IL2) cytokine subfamily. IL2 is produced by activated CD4+ and CD8+ T lymphocytes and is essential for the proliferation of T cells and B lymphocytes.
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Cat. No.: HY-W133907
CAS No.: 55566-30-8
Tetrakis (hydroxymethyl) phosphonium sulfate is a protein crosslinker and hydrogel modifier. Tetrakis (hydroxymethyl) phosphonium sulfate covalently binds to primary and secondary amines of amino acids or proteins via a Mannich-type reaction, thereby constructing stable crosslinking bonds between protein molecules. Tetrakis (hydroxymethyl) phosphonium sulfate not only regulates the gelation time and storage modulus of recombinant elastin-like protein hydrogels, but also exhibits excellent cytocompatibility, and supports the differentiation and growth of embryonic stem cells and neural cells in a three-dimensional encapsulation environment. Tetrakis (hydroxymethyl) phosphonium sulfate is suitable for protein-based hydrogel systems, especially for applications related to cell encapsulation .
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Cat. No.: HY-188105
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL10 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL10 mRNA. Human IL10 mRNA is the messenger ribonucleic acid encoding human IL-10. IL-10 mRNA expression is highly inducible and cell type specific.
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Cat. No.: HY-P11822
Research Areas:  

Infection

Py-FGGK is a gelatinase-responsive short peptide. Py-FGGK can specifically target MRSA, cause leakage of cellular components, generate ROS in situ, and kill biofilm-encapsulated MRSA cells. Py-FGGK can promote cell migration to aid wound healing, and accelerates wound healing in MRSA-infected rat models. Py-FGGK can be used in studies related to MRSA infection .
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Cat. No.: HY-185389
Synonyms: Liposomal cisplatin
Research Areas:  

Cancer

Cisplatin liposome is a liposome-encapsulated form of Cisplatin (HY-17394). Cisplatin (CDDP) is an anti-tumor chemotherapeutic agent that cross-links with DNA, causing DNA damage in cancer cells. Cisplatin liposome prolongs drug circulation time and slowly releases the drug, allowing it to accumulate in the tumor and exert its killing effect.
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Cat. No.: HY-P11759
Target:  

Drug Derivative

Research Areas:  

Cancer

Myr-transportan-Cys is a derivative of the cell-penetrating peptide Transportan (HY-P1732), and its conjugated myristoyl group (Myr) enhances the interaction between the peptide and cell membranes. Myr-transportan-Cys integrates three key delivery functions: nucleic acid condensation, cell penetration, and endosomal escape. Myr-transportan-Cys can form immunostimulatory tandem peptide nanocomplexes (iTPNCs) for encapsulating and delivering immunostimulatory oligonucleotide cargos to tumors .
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Cat. No.: HY-W1052178
Synonyms: Folate-PEG2000-Cholesterol
FA-PEG2000-Cholesterol (Folate-PEG2000-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .
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Cat. No.: HY-W1052178A
Synonyms: Folate-PEG3400-Cholesterol
FA-PEG3400-Cholesterol (Folate-PEG3400-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .
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Cat. No.: HY-W1052178B
Synonyms: Folate-PEG5000-Cholesterol
FA-PEG5000-Cholesterol (Folate-PEG5000-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .
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Cat. No.: HY-W1052178C
Synonyms: Folate-PEG10000-Cholesterol
FA-PEG10000-Cholesterol (Folate-PEG10000-Cholesterol) is a multifunctional drug delivery system composed of Folic acid (HY-16637), polyethylene glycol (PEG), and Cholesterol (HY-N0322). Folic acid (FA) has a high affinity for folic acid receptors and can be used to target cell membrane receptors for drug delivery. Cholesterol can improve the circulation time of encapsulated drugs .
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