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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
53 Results for "
APJ
" in MedChemExpress (MCE) Product Catalog:
Products (53)
53 Results for "APJ" in MCE Product Catalog:
Cat. No.: HY-P5392A
Target:
Research Areas:
Cat. No.: HY-P5392
CAS No.: 942905-20-6
Target:
Research Areas:
Cat. No.: HY-P703479
Synonyms: APLNR; APJ (Apelin) Receptor; Prev. AGTRL1; G Protein-Coupled Receptor APJ; APJ; G-Protein Coupled Receptor APJ; APJR; HG11 Orphan Receptor; G-Protein Coupled Receptor HG11; APJ Receptor; Angiotensin II Receptor-Like 1; HG11; Angiotensin Receptor-Like 1;
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704094
Purity: ≥ 95%, as determined by HPLC.
Synonyms: APLNR; APJ (Apelin) Receptor; Prev. AGTRL1; G Protein-Coupled Receptor APJ; APJ; G-Protein Coupled Receptor APJ; APJR; HG11 Orphan Receptor; G-Protein Coupled Receptor HG11; APJ Receptor; Angiotensin II Receptor-Like 1; HG11; Angiotensin Receptor-Like 1;
Species:
Human
Source:
HEK293
Cat. No.: HY-P705991
Purity: ≥ 95%, as determined by HPLC.
Synonyms: APLNR; APJ (Apelin) Receptor; Prev. AGTRL1; G Protein-Coupled Receptor APJ; APJ; G-Protein Coupled Receptor APJ; APJR; HG11 Orphan Receptor; G-Protein Coupled Receptor HG11; APJ Receptor; Angiotensin II Receptor-Like 1; HG11; Angiotensin Receptor-Like 1;
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-181540
Target:
Research Areas:
YL-GB063 is an Apelin receptor (APJ) antagonist. YL-GB063 inhibits Apelin-induced APJ β-arrestin recruitment (IC50 of 3.1 μM in HTLA cells). YL-GB063 has anti-cancer activity against ovarian cancer .
Cat. No.: HY-103080R
CAS No.: 1586787-08-7
Research Areas:
CMF019 (Standard) is the analytical standard of CMF019 (HY-103080). This product is intended for research and analytical applications. CMF019 is an orally active, potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents . Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. CMF019 is promising for research of chronic diseases, such as, pulmonary arterial hypertension .
Cat. No.: HY-179553
Target:
Research Areas:
(E)-ML233 is the E isomer of ML233 (HY-125976). ML233 is a potent APJ agonist .
Cat. No.: HY-103254R
CAS No.: 877636-42-5
Research Areas:
ML221 (Standard) is the analytical standard of ML221 (HY-103254). This product is intended for research and analytical applications. ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.
Cat. No.: HY-P700658
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APLN; APEL; Apelin; Apelin, AGTRL1 Ligand; XNPEP2; AGTRL1 Ligand; APJ Endogenous Ligand
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
