271 Results for "

CD4

" in MedChemExpress (MCE) Product Catalog:
Products (271)

271 Results for "CD4" in MCE Product Catalog:

Cat. No.: HY-W181026
CAS No.: 1197834-98-2
Target:  

Fluorescent Dye

Research Areas:  

Inflammation/Immunology

KLF10-IN-1 (#48-15) is a KLF10 inhibitor with an IC50 value of 40 μM for KLF10 reporter gene. KLF10-IN-1 can inhibit KLF10-DNA binding and transcriptional activity, block the conversion of CD4+CD25 T cells to CD4+CD25+T regulatory cells, and inhibit the expression of KLF10 target genes. KLF10-IN-1 can be used as a useful mechanistic probe to study KLF10-mediated effects and T regulatory cell biology .
loading...
    loading...
Cat. No.: HY-P99999

Target:  

HIV

Research Areas:  

Infection

Anti-Mouse CD4 Antibody (YTS 191) is anti-mouse CD4 IgG2b antibody inhibitor derived from host Rat.
loading...
    loading...
Cat. No.: HY-P990861
Anti-CD4 Antibody (OKT-4) is a kind of mouse IgG2b κ chimeric antibody inhibitor, targeting to human CD4. Anti-CD4 Antibody (OKT-4) can deplete T cells. Anti-CD4 Antibody (OKT-4) can be used for the researches of cancer, infection and immunology, such as melanoma and adenovirus infection .
loading...
    loading...
Cat. No.: HY-P99790
CAS No.: 147191-91-1
Synonyms: CEN 000029; cM-T412

Research Areas:  

Inflammation/Immunology

Priliximab (CEN 000029) is an anti-CD4 humanized monoclonal antibody. Priliximab binds to CD4 on the surface of T cells, resulting in a significant and sustained reduction in circulating CD4 + T cells. Priliximab can be used in research of rheumatoid arthritis (RA) .
loading...
    loading...
Cat. No.: HY-P99028
CAS No.: 680188-33-4
Synonyms: TMB-355; TNX-355

Target:  

HIV

Research Areas:  

Infection

Ibalizumab (TMB-355) is a humanized anti-CD4 IgG4 monoclonal antibody. Ibalizumab prevents HIV cell entry by binding to CD4 receptor. Ibalizumab can be used for the research of infection, such as HIV-1 infection .
loading...
    loading...
Cat. No.: HY-P99680
CAS No.: 174722-30-6
Synonyms: SB-210396; IDEC CE9.1

Target:  

Interleukin Related

Research Areas:  

Cancer

Keliximab (SB-210396) is a chimeric human/macaque IgG1 anti-CD4 monoclonal antibody with a Ki value of 1.0 nM for soluble CD4. Keliximab blocks T cell proliferation and inhibits IL-2 production. Keliximab can be used for cancer research .
loading...
    loading...
Cat. No.: HY-P5425
CAS No.: 126779-13-3
Target:  

Others

Research Areas:  

Others

Tetanus Toxin (830–844) is a biological active peptide. (tetanus toxin-derived peptide TT830–844 CD4+ T-cell epitope. This promiscuous CD4+ T-cell epitope can bind to a wide range of HLA–DRB molecules and is thus expected to activate CD4+ T-cell responses in a large part of the human population)
loading...
    loading...
CD4 aptamer sodium
0 Images
DNA, 5′-ATCCAGAGTGACGCAGCACCACCACCGTACAATTCGCTTTCTTTTTTCATTACCTACTCTGGCTGGACACGGTGGCTTAGT-3′, sodium salt
Cat. No.: HY-177822
CD4 aptamer sodium is a single-strand DNA aptamer that targets CD4. It significantly blocks the interaction between viral gp120 and CD4-expressing cells
loading...
    loading...
Cat. No.: HY-P99607
CAS No.: 182912-58-9
Synonyms: IDEC-151

Target:  

HIV

Research Areas:  

Inflammation/Immunology

Clenoliximab (IDEC-151) is a macaque-human chimeric monoclonal antibody (immunoglobulin G4) specific for the CD4 molecule on the surface of T lymphocytes. Clenoliximab can be used for the research of rheumatoid arthritis .
loading...
    loading...
Cat. No.: HY-RS02245
Research Areas:  

Others

CD4 Human Pre-designed siRNA Set A contains three designed siRNAs for CD4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS16540
Research Areas:  

Others

Cd4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P990353
Synonyms: TRX1

Research Areas:  

Inflammation/Immunology

Anti-CD4 Antibody (TRX1) is a humanized antibody expressed in CHO cells that targets CD4. Anti-CD4 Antibody (TRX1) has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-CD4 Antibody (TRX1) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
loading...
    loading...
Cat. No.: HY-P0272A
CAS No.: 1610056-01-3
Target:  

HIV

Research Areas:  

Infection

Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.
loading...
    loading...
Cat. No.: HY-W795993
CAS No.: 10245-44-0
Research Areas:  

Inflammation/Immunology

TJU103 is a CD4 inhibitor. TJU103 inhibits autoreactive CD4 + T cells by disrupting the function of the CD4 during activation. TJU103 decreases mononuclear cell infiltration in brain and spinal cord tissue of experimental allergic encephalomyelitis (EAE) mice model. TJU103 downregulates Th1 and Th2 cytokine levels in response to proteolipid protein epitope 139-151 (PLPe) and exhibits inhibitory effects both after the appearance of EAE symptoms and upon rechallenge with Ag. TJU103 can be used for autoimmune diseases like EAE and sclerosis (MS) research .
loading...
    loading...
Cat. No.: HY-P99495
CAS No.: 156586-90-2
Synonyms: RWJ 49004

Target:  

HIV

Research Areas:  

Inflammation/Immunology

Cedelizumab (RWJ 49004) is a IgG4 monoclonal antibody targeting CD4. Cedelizumab has immunosuppressant properties .
loading...
    loading...
Cat. No.: HY-P991643

Research Areas:  

Inflammation/Immunology

MTRX1011A is a humanized IgG1 monoclonal antibody inhibitor targeting CD4. MTRX1011A can be used for rheumatoid arthritis (RA) research .
loading...
    loading...
Cat. No.: HY-14135
CAS No.: 452296-83-2
Synonyms: BMS 043
Target:  

HIV

Research Areas:  

Infection Inflammation/Immunology

BMS 488043 (BMS 043) is an orally active and well-tolerated inhibitor of the attachment of human immunodeficiency virus type 1 (HIV-1) to CD4+ lymphocytes .
loading...
    loading...
Cat. No.: HY-W060417
CAS No.: 1019158-02-1
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

iST2-1 is an Stimulation-2 (ST2) inhibitor with an IC50 value of 46.65 μM, blocks interaction between ST2 and IL-33, inhibits downstream signaling. iST2-1 functions as an immunomodulator, reduces proliferation of CD4 + and CD8 + T cells, increases regulatory T cell populations, reduces IFN-γ +CD4 + T cell populations, increases Foxp3 +CD4 + regulatory T cell populations in the gastrointestinal tract. iST2-1 reduces plasma soluble ST2 and IFN-γ levels, reduces graft-versus-host disease scores, improves survival in graft-versus-host disease animal models, preserves graft-versus-tumor effect. iST2-1 can be used for the research of graft-versus-host disease .
loading...
    loading...
Cat. No.: HY-P991824

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD4 Antibody (YTS 177) reacts with the mouse CD4. Anti-Mouse CD4 Antibody (YTS 177) shows non-depleting but binding does induce rapid internalization of CD4 on both CD4 + Foxp3- T cells and Foxp3 + regulatory T cells. Recommend Isotype Controls: Rat IgG2a kappa, Isotype Control (HY-P990679) .
loading...
    loading...
Cat. No.: HY-P11802
CAS No.: 126144-46-5
Target:  

HIV

Research Areas:  

Infection

CD4 (81-92) (human) is a fragment of hCD4. CD4 (81-92) (human) can undergo structural modifications including derivatization and cyclization to enhance antiviral potency and stability, with sequence alterations affecting its activity. CD4 (81-92) (human) is applicable to studies related to HIV-1 infection .
loading...
    loading...