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Ibalizumab

(Synonyms: TMB-355; TNX-355)
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Based on 1 Customer Validation

Ibalizumab (TMB-355) is a humanized anti-CD4 IgG4 monoclonal antibody. Ibalizumab prevents HIV cell entry by binding to CD4 receptor. Ibalizumab can be used for the research of infection, such as HIV-1 infection.

For research use only. We do not sell to patients.

  • Purity : 99.74%
  • CAS No.: 680188-33-4
  • Molecular Weight:147.36 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ibalizumab
  • Experimental Validation Results for Ibalizumab
  • Experimental Validation Results for Ibalizumab
  • Ibalizumab Chemical Structure
    Ibalizumab Chemical Structure
CAS No.: 680188-33-4
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Ibalizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
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Top Publications Citing

Use of MCE Products

All HIV Isoforms

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100 mg

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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized huCD4-ECD can bind Ibalizumab. The EC50 for this effect is 3.922 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 THP-1 cells with Ibalizumab (HY-P99028, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control.

  • Ibalizumab Chemical Structure
    1/16
  • Ibalizumab
  • Immobilized huCD4-ECD can bind Ibalizumab. The EC50 for this effect is 3.922 ng/mL.
  • Flow cytometric analysis of 1.5X106 THP-1 cells with Ibalizumab (HY-P99028, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control.