Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
75 Results for "
GLUT4
" in MedChemExpress (MCE) Product Catalog:
Products (75)
75 Results for "GLUT4" in MCE Product Catalog:
Cat. No.: HY-170943
Research Areas:
Antidiabetic agent 7 (Compound 5m) is hyperglycemic inhibitor. Antidiabetic agent 7 exhibits promising potency to stimulate GLUT4 translocation in skeletal muscle cells via activating AMPK-dependent pathway. Antidiabetic agent 7 reduces blood glucose levels. Antidiabetic agent 7 shows favorable pharmacokinetic properties. Antidiabetic agent 7 is potential to be used for anti-hyperglycemic research .
Cat. No.: HY-113402AR
CAS No.: 283159-88-6
Synonyms: γ-Glu-Cys TFA (Standard)
Category:
Cat. No.: HY-133559
CAS No.: 1854008-12-0
Target:
Research Areas:
VSP-77 is an orally active PPARγ agonist. VSP-77 selectively upregulates the expression of insulin sensitivity-related genes (Glut4 and Adiponectin) by inhibiting CDK5-mediated phosphorylation of PPARγ at Ser-273. VSP-77 significantly improves glucose tolerance, reduces fasting blood glucose and insulin levels in high-fat diet (HFD)-induced diabetic mouse models. VSP-77 can be used for the study of diabetes .
Cat. No.: HY-123547
CAS No.: 309932-60-3
Target:
Research Areas:
TLK19781 is a non-peptide small molecule insulin receptor activator that increases the content of insulin-stimulated GLUT4 on the cell membrane and enhances the activity of insulin-stimulated glucose transport in cell and animal models of insulin resistance.
Cat. No.: HY-W010736S
CAS No.: 1872379-48-0
Target:
Research Areas:
1,2-Dipalmitoyl-sn-glycerol-d9 is the deuterated-labeled 1,2-Dipalmitoyl-sn-glycerol (HY-W010736). 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that activates PKC. 1,2-Dipalmitoyl-sn-glycerol promotes GLUT4 translocation to the cell surface and recruitment to the plasma membrane of adipocytes. 1,2-Dipalmitoyl-sn-glycerol can be used in research on type 2 diabetes [4] .
Cat. No.: HY-W010736R
CAS No.: 30334-71-5
Category:
Target:
Target:
Target:
Cat. No.: HY-101849R
CAS No.: 392721-37-8
Target:
Research Areas:
Fasentin (Standard) is the analytical standard of Fasentin. This product is intended for research and analytical applications. Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity .
Cat. No.: HY-123765
CAS No.: 701232-94-2
Target:
Research Areas:
JTT-553 is a DGAT1 inhibitor (IC50: 2.38 nM). JTT-553 reduces plasma concentrations of glucose, insulin, non-esterified fatty acids (NEFA), total cholesterol (TC), and hepatic triglycerides (TG). JTT-553 improves insulin-dependent glucose uptake and glucose intolerance in adipose tissue of DIO mice. JTT-553 reduces TNF-α mRNA levels and increases GLUT4 mRNA levels in adipose tissue of KK-Ay mice. JTT-553 improves adipose tissue insulin resistance and systemic glucose metabolism by reducing body weight. JTT-553 can be used in the study of obesity and type 2 diabetes mellitus (T2DM) .
Cat. No.: HY-142444
CAS No.: 2647975-06-0
Target:
Research Areas:
SSAO/VAP-1 inhibitor 1 is a potent inhibitor of SSAO/VAP-1. SSAO/VAP-1 promotes the transfer of Glucose transport 4 (GLUT 4) from adipocytes to the cell membrane, thereby regulating glucose transport. In endothelial cells, SSAO/VAP-1 can mediate the adhesion and exudation of leukocytes and endothelial cells, and participate in inflammatory responses. SSAO/VAP-1 inhibitor 1 has the potential for the research of inflammation and/or inflammation-related disease or diabetes and/or diabetes-related disease (extracted from patent WO2021102774A1, compound E3) .
Cat. No.: HY-N0755R
CAS No.: 17306-46-6
Category:
Cat. No.: HY-P86894
Synonyms: insulin-responsive antibody; Glucose transporter GLUT 4 antibody; Glucose transporter type 4 antibody; Glucose transporter type 4 insulin responsive antibody; GLUT 4 antibody; GLUT-4 antibody; GLUT4 antibody; GTR4_HUMAN antibody; Insulin responsive glucose transporter type 4 antibody; kug antibody; insulin-responsive antibody; Glucose transporter GLUT 4 antibody; Glucose transporter type 4 antibody; Glucose transporter type 4 insulin responsive antibody; GLUT 4 antibody; GLUT-4 antibody; GLUT4 antibody; GTR4_HUMAN antibody; Insulin responsive glucose transporter type 4 antibody; kug antibody; SLC 2A4 antibody; SLC2A4 antibody; solute carrier family 2 (facilitated glucose transporter) member 4 antibody; Solute carrier family 2 member 4 antibody; Solute carrier family 2, facilitated glucose transporter member 4 antibody;
Cat. No.: HY-137677
CAS No.: 37589-80-3
Synonyms: Guanosine 5'-[γ-thio]triphosphate
Target:
Research Areas:
GTPγS (Guanosine 5'-[γ-thio]triphosphate) is a G-protein activator that protects proteins from proteolytic degradation, stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization. GTPγS to couple with G- protein α, to study its effect on kinase activity. GTPγS acts as a component of lysis buffer [4].
Cat. No.: HY-D3199
CAS No.: 2364376-61-2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
