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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
64 Results for "
Protein thiol groups
" in MedChemExpress (MCE) Product Catalog:
Products (64)
64 Results for "Protein thiol groups" in MCE Product Catalog:
Cat. No.: HY-D1404
CAS No.: 2100286-15-3
Cat. No.: HY-D1407
CAS No.: 2468100-37-8
Cat. No.: HY-152919
CAS No.: 2387738-43-2
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Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure.
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Dichlorophen (Standard) is the analytical standard of Dichlorophen (HY-12638). This product is intended for research and analytical applications. Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections .
Cat. No.: HY-W591469
Cat. No.: HY-D3565
Cat. No.: HY-D3568
Cat. No.: HY-D3579
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AF568 C5 Maleimide is a bright orange-red thiol-reactive fluorescent dye. AF568 C5 Maleimide selectively labels the thiol groups on cysteine residues in proteins, peptides and antibodies via stable thioether bonds (Ex/Em = 575/600 nm) .
Cat. No.: HY-D3342
Cat. No.: HY-W591360
CAS No.: 1240737-77-2
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Iodoacetamido-PEG6-azide is an aqueous soluble PEG linker containing an azide and a terminal Iodoacetamido group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Iodoacetamido moiety is commonly used to bind covalently with the thiol group of cysteine so the protein cannot form disulfide bonds.
Cat. No.: HY-D2763
CAS No.: 890928-51-5
Cat. No.: HY-D3573
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AF488 C5 Maleimide is a thiol-reactive Fluorescent dye used to label target proteins and bacterial structures. AF488 C5 Maleimide irreversibly forms covalent thioether conjugates with cysteine thiol groups. AF488 C5 Maleimide stabilizes pre-formed globular low-molecular-weight Tau protein oligomers by blocking cysteine-dependent tau protein aggregation, allowing observation of the internalization process of tau protein oligomers into neuronal cells via confocal microscopy. AF488 C5 Maleimide can label cysteine-modified pili; the outer membrane permeability varies among different bacterial species, allowing imaging via epifluorescence microscopy using a FITC filter set .
Cat. No.: HY-W578278
CAS No.: 535943-48-7
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tert-Butyl (2-(pyridin-2-yldisulfanyl)ethyl)carbamate consists of a tert-butyl group, where the protected amine can be deprotected under mild acidic conditions, and the other part of the molecule may act as a thiol-specific labeling reagent, commonly used in reversibly binding cysteine residues on proteins.
Cat. No.: HY-D3512
Cat. No.: HY-D3513
Cat. No.: HY-D3514
Cat. No.: HY-D3527
Cat. No.: HY-D3528
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
