54 Results for "

cell surface antigens

" in MedChemExpress (MCE) Product Catalog:
Products (54)

54 Results for "cell surface antigens" in MCE Product Catalog:

Cat. No.: HY-D3276
Target:  

Fluorescent Dye

Research Areas:  

Others

PE-Cy7 is a tandem dye conjugate based on fluorescence resonance energy transfer (FRET). Composed of phycoerythrin (PE) as the donor and Cy7 as the acceptor fluorescent dye, PE-Cy7 is suitable for multicolor flow cytometry, laser scanning cytometry and immunofluorescence applications. PE-Cy7 can be conjugated to antibodies or used in the biotin-streptavidin system to label cell surface antigens in immunophenotyping and multiparametric cell analysis. PE-Cy7 undergoes photon-induced oxidative degradation, whose rate depends on light intensity and storage conditions, leading to reduced FRET efficiency and increased PE leakage. PE-Cy7 can be excited at wavelengths of 488 nm, 532 nm or ~760 nm, and its emission signal can be detected using 780/60 nm, 810/90 nm or 785/50 nm bandpass filters, with a Stokes shift of 300 nm .
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Cat. No.: HY-P992317

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

ATL301 is a human monoclonal antibody that targets human ganglioside GD2 (ganglioside GD2). GD2 is a highly expressed glycolipid antigen on the surface of neuroepithelial tumor cells, and is commonly found in neuroblastoma, melanoma, osteosarcoma, small cell lung cancer, etc.
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Cat. No.: HY-P991844

Target:  

CD74

Research Areas:  

Inflammation/Immunology

Anti-HLA-DQ Antibody (1a3) reacts with human HLA-DQ. HLA-DQ (DQ) is a cell surface receptor protein found on antigen-presenting cells. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978) .
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Cat. No.: HY-P992111
CAS No.: 3058391-18-4
Synonyms: UCB4594

Target:  

MHC

Research Areas:  

Cancer

Elfritatug (UCB4594) is a humanized monoclonal antibody targeting human leukocyte antigen-G (HLA-G). By binding to HLA-G on the surface of tumor cells, Elfritatug blocks its immunosuppressive effect, thereby enhancing the body's immune response against tumors .
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Cat. No.: HY-181347
CAS No.: 2346450-55-1
Target:  

HBV

Research Areas:  

Infection

GLPG3808 is an orally active PAPD5/7 inhibitor. GLPG3808 inhibits the expression of HBcAg in various cells infected with HBV. GLPG3808 reduces the hepatitis B surface antigen levels in HBV-infected animal models. GLPG3808 can be used for the research of hepatitis B virus infection .
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Cat. No.: HY-185967
Target:  

mRNA

Research Areas:  

Others

CD19 mRNA (N1-methyl-pseudouridine) encodes the B cell surface antigen CD19, used in CAR-T cell research and immunological studies. CD19 plays two main functions in human B cells: as an aptamer protein, recruiting cytoplasmic signaling proteins to the cell membrane; and within the CD19/CD21 complex, lowering the activation threshold of B cell receptor signaling pathways.
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Cat. No.: HY-P99843A

Target:  

TROP2 ADC Antibodies

Research Areas:  

Cancer

Datopotamab (powder) is a humanized anti trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab (powder) can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab (powder) can be used in the study of triple negative breast cancer and non-small cell lung cancer .
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Cat. No.: HY-P992362

Target:  

CD73

Research Areas:  

Cancer

HBM1007 is a fully human monoclonal antibody targeting CD73. HBM1007 is an extracellular enzyme expressed on the surface of stromal cells and tumor cells, capable of converting extracellular adenosine monophosphate (AMP) into adenosine, and recognizing CD73 via a unique antigenic epitope. HBM1007 inhibits both CD73-dependent and CD73-independent enzyme activities.
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Cat. No.: HY-126970R
CAS No.: 957011-15-3
Target:  

HBV

Research Areas:  

Infection

HBF-0259 (Standard) is the analytical standard of HBF-0259. This product is intended for research and analytical applications. HBF-0259 is a potent and selective inhibitor of hepatitis B virus (HBV) surface antigen (HBsAg) secretion, with an EC50 of 1.5 μM in HepG2.2.15 cells. HBF-0259 has no effect on HBV DNA synthesis .
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Cat. No.: HY-N17893
CAS No.: 1831153-21-9
Swertiachoside B (compound 4) is a tetrahydroxanthone glycoside (3-nortetrahydroswertiamarin) that occurs throughout the whole plant of Swertia chirayita .
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Cat. No.: HY-P992062

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD80 Antibody (TKMG48) is an antibody that targets mouse CD80. By specifically binding to and disrupting the CD80:PD-L1 complex to release PD-L1, Anti-Mouse CD80 Antibody (TKMG48) functions as an indirect PD-1 agonist without blocking CD28 co-stimulation or CD80-CTLA4 binding. Anti-Mouse CD80 Antibody (TKMG48) inhibits T cell activation, reduces T cell effector functions and antigen-specific CD8 + T cell populations, and does not interfere with the differentiation, migration, antigen presentation or surface marker expression of dendritic cells. Anti-Mouse CD80 Antibody (TKMG48) significantly attenuates disease severity in mouse models of arthritis, spondyloarthritis, multiple sclerosis and Sjögren's syndrome, and its activity depends on the expression of PD-1 and PD-L1 .
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Cat. No.: HY-P991762

Research Areas:  

Inflammation/Immunology

Anti-Rat CD4 Antibody (W3/25) reacts with rat CD4. Anti-Rat CD4 Antibody (W3/25) inhibits CD4+ T cell activation by downregulating the CD4 molecule on the surface of lymphocytes. Anti-Rat CD4 Antibody (W3/25) inhibits antigen-induced T cell proliferation and IL2 production in MLR experiments. Anti-Rat CD4 Antibody (W3/25) can be used for the study of experimental allergic encephalomyelitis (EAE). Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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Cat. No.: HY-183576
Target:  

HBV

Research Areas:  

Infection Neurological Disease

HBsAg-IN-1 is an orally active, highly liver-selective inhibitor of HBsAg production, with an EC50 of 0.63 nM. HBsAg-IN-1 shows no neurite growth inhibitory activity. HBsAg-IN-1 can be used in studies related to hepatitis B virus (HBV) infection .
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Cat. No.: HY-P992159
Anti-ZnT8 Antibody (mAb43) is a monoclonal antibody targeting the zinc transporter ZnT8, with islet-specific biodistribution characteristics. Anti-ZnT8 Antibody (mAb43) binds to extracellular ZnT8 on the surface of pancreatic β-cells and masks its insulin-co-localizing sites to block autoimmune recognition. Anti-ZnT8 Antibody (mAb43) also promotes an increase in the proportion of regulatory T cells and inhibits B cell antigen presentation, thereby effectively blocking the T cell-mediated cascade of β-cell destruction. Anti-ZnT8 Antibody (mAb43) eliminates insulitis, preserves β-cell mass and induces seroconversion of autoantibodies, without directly altering the insulin secretion function or content of β-cells. Anti-ZnT8 Antibody (mAb43) can be used for research related to type 1 diabetes .
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